ATI RN PHARMACOLOGY FOR NURSING
EDITION 6.0
Ondansetron hydrochloride - ANS (Zofran) Antiemetic helps with nausea and vomiting
Fluconazole - ANS (Diflucan) can treat and prevent fungal infections (oral thrush)
Aripiprazole - ANS (Abilify) antipsychotic treats schizophrenia, bipolar, depression, and Tourette
syndrome. can also treat irritability with autism.
phenytoin - ANS (Dilantin) Anticonvulsants treats and prevents seizures
What should you avoid when taking MAOIs - ANS Foods containing tyramine such as cheese
and processed meats, smoked fish, pepperoni, salami, avocados, figs, bananas, protein dietary
supplements, soups, soy sauce, some beers, and red wine. Can lead to a hypertensive crisis!!!
When taking tetracycline what should you avoid - ANS Dairy products for 2 hrs. Tetracycline is
an antibiotic that treats acne and skin infections. (chlamydia, cholera, Rosacea, anthrax,
stomach ulcer)
Use caution with Grapefruit Juice - ANS can act by inhibiting medication metabolism in the
small bowel and increase the amount of medication available for absorption.
Morphine - ANS Causes respiratory depression so avoid use in clients with asthma or impaired
respiratory function.
warfarin - ANS blood thinner and is a category X medication for pregnancy
oxycodone and Ibuprofen - ANS oxycodone is a narcotic analgesic and ibuprofen is an NSAID.
They work by different mechanisms, but pain is better relieved when they are taken together.
Gentamicin - ANS Narrow-spectrum aminoglycoside antibiotic used to treat serious infections
caused by aerobic bacilli. Can Cause renal issues... monitor labs
SSRI Selective serotonin reuptake inhibitors
*TAKE IN THE AM - minimize sleep disturbance - ANS Fluoxetine (Prozac)
Citalopram (celexa)
Escitalopram (Lexapro)
paroxetine (Paxil)
, sertraline (Zoloft)
Vilazodone (Viibryd)
SSRI's selectively black reuptake of the monoamine neurotransmitter serotonin in the synaptic
space, thereby intensifying the effects of serotonin.
Used with anxiety/depression
-Major Depression
-OCD
-Bulimia nervosa
-premenstrual dysphoric disorders
-panic disorders
-PTSD
Category C for pregnancy - ANS sexual dysfunction
CNS Stimulation- inability to sleep, agitation, anxiety
weight loss/gain
Serotonins syndrome- many begin 2-72 hr ( mental confusion, fever, agitation, anxiety,
hallucinations, incoordination, diaphoresis, tremors.)
Withdrawal syndrome- taper dose
faintness/lightheadedness
GI Bleeding
Bruxism- grinding teeth
*don't take with MAOI or tricyclic antidepressants TCA's, or St. John's Wort
Need to wait 14 days
fluoxetine SSRI wait 5 weeks before an MAOI
Fluoxetine (SSRI) - ANS -can displace warfarin and increase levels (need to monitor the clients
PT and INR levels)
-can increase levels of tricyclic antidepressants and lithium
-it suppresses platelet aggregation and causes increased risk for bleeding when used with
NSAIDS and anticoagulants.
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