100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
farmacologie partim 1 overzicht $6.60   Add to cart

Class notes

farmacologie partim 1 overzicht

 3 views  0 purchase
  • Course
  • Institution

farmacologie partim 1 overzicht (volgorde les)

Preview 3 out of 18  pages

  • September 26, 2024
  • 18
  • 2023/2024
  • Class notes
  • Guns en demeyer
  • All classes
avatar-seller
Farmacon Receptor Indicatie Effect/Functie Nevenwerkingen/Info
Acetylcholine* Muscarine agonist Myasthenia Gravis? Cardiale inhibitie, ↑ Snelle inactivatie via AChE
kliersecretie, miosis, ↑ GIS Nw: braken, diarree, bronchoconstrictie
motiliteit, blaascontr,
bradycardie, hypotensie
Carbachol* Muscarine + nicotine agonist Oogheelkunde Cardiale inhibitie, ↑ Bestand tegen AChE
kliersecretie, miosis, ↑ GIS
=direct Nw: braken, diarree, bronchoconstrictie
motiliteit
parasympathicometicum
Pilocarpine Muscarine agonist Glaucoom (oogdruppels) Miosis, betere afvoer Geringe activiteit in hart en GIS
oogvocht
Partiele mAch agonsist
MUSCARINE ANTAGONIST M1 neuraal Anti-emeticum Cytoplegie en miosis Accomodatie verlamming  wazig zicht

 CZS, ganglia ↑ Oogdruppels Speekselvloed, tranen Afname kliersecretie  droge mond
 maagzuursecretie↑ Pre-anesthesie Tachycardie
Bradycardie en hypotensie
M2 hart Sinus bradycardie Bronchodilatatie
Bronchoconstictie
Astma/COPD Daling motiliteit  constipatie
 Hart ↓
GI spasmen Peristatiek GI (spasmen)
 Presynaptische Verslapping GSC  urine retentie
afgifte ↓ Overactieve blaas Blaascontractie Geheugenstoornissen
(CAVE prostaatlijden) (incontinentie)
M3 klieren
CONTRAINDICATIE:
 Klieren
 Gladde spiercellen Glaucoom
 EC prostaatlijden

Hyoscine (scopolamine) Muscarine antagonist Wagenziekte, braken bij
(competitief) reisziekte
Butyl scopolamine* Muscarine antagonist GI hypermotiliteit GI motiliteit ↓
(=buscopan) (competitief) spasmen




1

, Farmacon Receptor Indicatie Effect/Functie Nevenwerkingen/Info
Atropine Muscarine antagonist Premedicatie anesthesie Ook in CZS Wazig zicht bij pupilverwijding door
(competitief) pupilverwijding accomodatieverlamming
Tachycardie, ↓
sinus bradycardie kliersecretie, mydriasis, ↓
Parkinson GIS motiliteit, verslapping
GSC (bronchi, urineweg,
galweg)
Ipratropium bromide* Muscarine antagonist Astma, bronchitis, COPD Verslapping gladde Inhalatie bij bronchospasmen
spiercellen van bronchiën
NICOTINE nAChR (kationkanalen dus Niet gebruikt als medicatie Lage dosis=stimulatie
werken snel) (agonist)
Hoge dosis= desensitisatie
(antagonist)

AANGRIJPINGSPUNTEN
Neuromusculaire
overgang
Ganglia AZS (BHB)
CZS (BHB)
Vrijgave adrenaline in de
bijnier
Suxamethonium * nAChR agonist Spierverslappers bij Depolarisatie blok in 2
(succinylcholine) anesthesie fases
perifere werking, kort
Fasiculaire contracties
effect versterkt door AChE
remmers




Atracurium* Nicotine antagonist Spierverlamming bij Transiënte hypotensie, AchE remmer heft effect op

2

, Farmacon Receptor Indicatie Effect/Functie Nevenwerkingen/Info
=d-tubocurarine (competitief) anesthesi spierverlamming
(transmissie blokkade)
spierverslapper; eerst oog,
aangezicht, dan CONTRA-INDICATIE
ledematen, farynx en finaal
Myasthenia gravis (minder receptoren)
ademhaling
CHOLINESTERASE Anesthesie Parasympatisch ZS Parasympatisch ZS
REMMERS  Galucoom  cholinerge crisis
Glaucoom
Ganglia autonome ZS
Neuromusculaire overgang
 depolarisatieblo: hypotensie en bradycardie
 Myasthenia gravis CZS
 opheffen  intoxicatie
transmissieblok
CAVE paradoxale
spierzwakte
Ziekte van Alzheimer
Vergifteging (parathion,
oorlogsgassen)

Fysostigmine Cholinesteraseremmer Glaucoom (in oogdruppel Betere afvoer van Indien extreme CZS (door BHB) stimulatie:
(indirecte voor lokaal effect) oogvocht convulsies, bewustloosheid en ademstilstand…
parasympathicomimetica) Alzheimer
Neostigmine* Cholinesteraseremmer Myasthenia Gravis, Beëindigen Cholinerge Crisis mogelijk: (Wazig zicht,
anesthesie transmissieblok speekselvloed, GIS-krampen) tegengaan met
atropine




3

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller biomed124. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $6.60. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

79373 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$6.60
  • (0)
  Add to cart