NUR 2474 Pharmacology Rasmussen Final Exam || With Questions & Solutions (Rated A+)
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Course
NURS 2474 - Rasmussen Pharmacology
Institution
NURS 2474 - Rasmussen Pharmacology
NUR 2474 Pharmacology Rasmussen Final Exam || With Questions & Solutions (Rated A+)
NUR 2474 Pharmacology Rasmussen Final Exam || With Questions & Solutions (Rated A+)
What are potential interactions for ASA and ibuprofen? - ANSWER - -Anticoagulants, glucocorticoids, and alcohol increase the ri...
NUR 2474
2024 Pharmacology
Rasmussen Final Exam
|| With Questions &
Solutions (Rated A+)
Conceptial Research ||
conceptialresearch@gmail.com
, NUR 2474 Pharmacology Rasmussen
Final Exam || With Questions &
Solutions (Rated A+)
What are potential interactions for ASA and ibuprofen? - ANSWER - -Anticoagulants,
glucocorticoids, and alcohol increase the risk of bleeding.
-Ibuprofen decreases the antiplatelet effects of low-dose ASA.
-ACE inhibitors and angiotensin receptor blockers increase the risk of kidney failure.
-Antihypertensive effect of ACE inhibitors decrease the risk of lithium carbonate
(Lithobid) and methotrexate toxicity increases.
What are the therapeutic uses for celecoxib? - ANSWER - -Inflammation
suppression
-Analgesia for mild to moderate pain
-Fever reduction
-Dysmenorrhea
What are the adverse drug reactions associated with celecoxib? - ANSWER - -GI
upset, heartburn, nausea, diarrhea, gastric ulceration (possibly less than w/ COX-1
inhibitors)
-Kidney dysfunction
-Cardiovascular and cerebrovascular events
What interventions should be planned for a client taking celecoxib? - ANSWER - -
Monitor for and report gastric upset, heartburn, nausea, diarrhea, or GI bleeding.
-Test for and treat H. pylori infection prior to long-term therapy.
-For clients at high risk for gastric bleeding, recommend a PPI.
-Monitor intake and output, watch for low urine output and fluid retention.
-Monitor for rapid rises in BUN and Creatinine.
-Recommend the drug for short periods and in low doses only.
-Recommend low-dose ASA to prevent these events.
-Monitor for signs of MI and CVA.
What admin considerations apply to celecoxib? - ANSWER - -Give 2 hr before or
after Mg or Al-based antacids.
-Monitor for initial and continued therapeutic effects.
What instructions should be provided for a client taking celecoxib? - ANSWER - -
Take w/ food, milk, or 8 oz of water to minimize GI effects.
-Avoid alcohol.
-Report persistent GI irritation and signs of bleeding.
-Report changes in urine output, weight gain, or signs of fluid retention such as
edema or bloating.
-Report chest pain or heaviness, SOB, sudden and severe headache, numbness,
weakness, visual disturbances, or confusion.
-Take low-dose ASA once daily to reduce the risk of heart attack and stroke.
, What contraindications are there for the use of celecoxib? - ANSWER - -Pregnancy
risk (third trimester); can cause premature closure of the ductus arteriosus.
-Severe hepatic impairment
-Advanced kidney disease
-Children younger then 18 yr
-GI bleeding
-Anemia
-Pain from coronary artery bypass grafting
-Allergy to sulfa, sulfonamides, celecoxib
What precautions are there for the use of celecoxib? - ANSWER - -Alcohol use
disorder
-Heart failure
-DM
-HTN
-Asthma
-Hx of GI bleeding or peptic ulcer disease
-Cardiovascular disease
-Mild or moderate liver impairment
-Renal insufficiency
-Cerebrovascular accident
What are potential interactions for celecoxib? - ANSWER - -Diuretic effects of
furosemide (Lasix) decrease.
-Fluconazole (Diflucan) increases celecoxib levels.
-Anticoagulant effects of warfarin (Coumadin) increase.
-Glucocorticoids and alcohol increase the risk of bleeding.
-Antihypertensive effects of ACE inhibitors decrease
-Risk of lithium carbonate (Lithobid) toxicity increases.
What are the therapeutic uses for acetaminophen? - ANSWER - Analgesia for mild
to moderate pain. Fever reduction.
What are the adverse drug reactions associated with acetaminophen? - ANSWER - -
Liver damage (overdose)
-HTN (with daily use, particularly women)
What interventions should be planned for a client taking acetaminophen? - ANSWER
- -Monitor for early Sx of overdose/poisoning (abdominal discomfort, nausea,
vomiting, sweating, diarrhea); liver damage results in 48-72 hr following overdose.
-Prepare to admin acetylcysteine (Mucomyst, Acetadote) orally or IV to counteract
overdose and reduce liver injury.
-Monitor BP.
What admin considerations apply to acetaminophen? - ANSWER - -Admin orally or
rectally.
-Caution clients that the drug is available in many combination products as well as
many combination products as well as many formulations; clients must read labels
carefully to avoid OD.
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