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MGG exam 11
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MGG exam 11Which sequence is present in the mature mRNA but not translated? - - UTR
- Which RNA polymerase transcribes rRNAs? - - RNA pol 1
- What must happen before RNA polymerase II will attach and begin to
transcribe mRNA? - - All of the promoter element sites must be bound by
their respective transcription factors
- Since there is no specific stop site in eukaryotic transcription, where do
you think they would label the end of an eukaryotic mRNA in the gene
graphic of a genome browser program? - - poly(A) site
- What is the first step in splicing out of an intron? - - The 2' OH of an
interior adenosine attacks the 5' splice site
- What are the consequences of alternative splicing? - - Different mRNA
variants can be made for different tissues from a single gene
- A "consensus sequence" is: - - a sequence comprising the most common
base in the population at each position
- What is a natural consequence of the development of paralogs? - - One of
the paralogs stays functional and the other is evolutionarily free to mutate
- When looking at the sequence of a pseudogene, how can you tell it was
derived via reverse transcription? - - poly(A) tract present and no introns or
promoter
- In globin evolution in mammals, several evolutionary events occurred.
Which of the following events did NOT occur? - - Reduction from a large set
to a smaller, more compact set of globins
- What does "LTR" stand for? - - long terminal repeat
- What happens to the viral RNA template in retroviral/LTR retrotransposon
replication? - - Viral RNase H degrades it during synthesis of the cDNA
strand
- The ends of the retroviral RNA are R-U5 at the 5' end and U3-R at the 3'
end. How are these converted to U3-R-U5 (LTR)? - - template switching
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