what are the factors affecting drug response? - Answers:pt wt
age
physiological state
time of day
pathological issue
immune response
accumulation
psychologic factors
tolerance
drug interactions
renal/hepatic function
what are the RN responsibilities with oral medications? - Answers:route: PO, sublingual, buccal
I: check ability to swallow, check on pt 45 min after admin
what should the RN do for inhalation meds? - Answers:teach the pt the proper technique fro
breathing
wash mouth after the use of med (protect teeth)
what should the RN do for intradermal meds? - Answers:assess skin before and after admin
rotate admin site
remove hair -proper absorption
what are the Rn responsibilites for injections? - Answers:proper technique
extra careful about dosage amt
assess 10-30min after admin
pharmacology - Answers:the medical study of medicine concerning the uses, effects, and mode
of action of drugs. Ie. Acetaminophen (Tylenol) is used to relieve mild to moderate pain. Its
, MOA is the inhibition of cyclooxygenase which blocks prostaglandin production and hampers
with pain impulse generation in the PNS. Some AD are hypotension, nausea and vomiting
ethnopharmacology - Answers:1. use of herbs, powders, teas and animal products as healing
remedies. Ie. Aloe vera is a antiinflammation and analgesic herb that can be used to treat rashes
and skin irritation.
Bioavailability - Answers:the rate at and the extent to which a nutrient is absorbed and used
biologics - Answers:these are manufactured living systems used for medical purposes. Ie.
Vaccines, blood and blood components, and allergenics
blood brain barrier (BBB) - Answers:This is the tight junction in btw the blood and brain vessels
in the brain. Ie. Gabapentin is a water-soluble drug that is able to cross the BBB and aids with
activating the CNS
therapeutic action - Answers:1. the desired effect of the drug. Ie. Diazepam is a drug with a
therapeutic action of inducing sedation.
adverse reaction - Answers:an unintentional/ unexpected rxn to the drug. Ie. An Adverse rxn to
amoxicillin are nausea, vomiting and diarrhea.
allergic reaction - Answers:when the immune system overreacts to a substance- there are 4 types.
Ie. If a pt is allergic to shellfish and takes glucosamine sulfate (a dietary supplement that is
contraindicated for shellfish and peanut allergies) then the pt starts to exhibit a rash or hives this
is an allergic rxn.(1 system)
anaphylaxis - Answers:an acute allergic reaction to an antigen (hypersensitivity). Ie. If I am
allergic to bees and get stung by one I will exhibit SOB, tachycardia, and a rash. (note: more than
1 body system involved
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