DPT FINAL EXAM
(COMPILED)
QUESTIONS WITH
ACTUAL ANSWERS!!
DPT
Evatee 9/28/24 DPT
,DPT FINAL EXAM (COMPILED) QUESTIONS
WITH ACTUAL ANSWERS!!
fibromyalgia is due to a deficit in the _________ inhibitory system Answer -
descending
increased excitatory NT in FM Answer - glutamate and substance P
gene alterations associated with pain sensitivity in FM Answer - COMT
alterations of DA and NE
gene alterations associated with metabolism, transport, and receptors for SE
implicated in FM Answer - SLC64A4, 5-HTT, 5-HT2aR and COMT
treatment of fibromyalgia Answer - cyclobenzaprine, TCA, SNRI, tramadol,
gabapentin, pregabalin
MOA of gabapentin and pregabalin Answer - bind to alpha 2 delta subunit of
Ca channels
MG has a ______ in the number of available AChRs Answer - decrease
immunoglobulins responsible for the anti-AChR antibodies Answer - IgG1 and
IgG3
immunoglobulin responsible for MuSK antibodies Answer - IgG4
, role of thymus in MG Answer - may trigger or maintain production of
antibodies
genetic factors in MG Answer - HLA types
drugs that trigger MG Answer - antibiotics (macrolides, fluoroquinolones,
tetracycline, chloroquine, aminoglycosides) anti arrhythmic (beta blockers, CCB,
quinidine, lidocaine, procainamide)
most common symptom of MG Answer - weakness of eye muscles
symptomatic treatment of MG Answer - pyridostigmine
MOA of pyridostigmine Answer - inhibit the cholinesterase enzyme and
increase the availability of Ach at the NMJ
what patients obtain less benefit from pyridostigmine Answer - patients with
anti-MuSK MG
how to reduce side effects of pyridostigmine Answer - lomotil or loperamide
MOA of glucocorticoids in MG Answer - anti-inflammatory,
immunosuppressive (inhibit T lymphocyte fxn), antiproliferative (inhibit DNA
synthesis)
mycophenolate mofetil MOA Answer - selective inhibition of purine synthesis
by the de novo pathway, inhibits proliferation of lymphocytes but not of other
cells
(COMPILED)
QUESTIONS WITH
ACTUAL ANSWERS!!
DPT
Evatee 9/28/24 DPT
,DPT FINAL EXAM (COMPILED) QUESTIONS
WITH ACTUAL ANSWERS!!
fibromyalgia is due to a deficit in the _________ inhibitory system Answer -
descending
increased excitatory NT in FM Answer - glutamate and substance P
gene alterations associated with pain sensitivity in FM Answer - COMT
alterations of DA and NE
gene alterations associated with metabolism, transport, and receptors for SE
implicated in FM Answer - SLC64A4, 5-HTT, 5-HT2aR and COMT
treatment of fibromyalgia Answer - cyclobenzaprine, TCA, SNRI, tramadol,
gabapentin, pregabalin
MOA of gabapentin and pregabalin Answer - bind to alpha 2 delta subunit of
Ca channels
MG has a ______ in the number of available AChRs Answer - decrease
immunoglobulins responsible for the anti-AChR antibodies Answer - IgG1 and
IgG3
immunoglobulin responsible for MuSK antibodies Answer - IgG4
, role of thymus in MG Answer - may trigger or maintain production of
antibodies
genetic factors in MG Answer - HLA types
drugs that trigger MG Answer - antibiotics (macrolides, fluoroquinolones,
tetracycline, chloroquine, aminoglycosides) anti arrhythmic (beta blockers, CCB,
quinidine, lidocaine, procainamide)
most common symptom of MG Answer - weakness of eye muscles
symptomatic treatment of MG Answer - pyridostigmine
MOA of pyridostigmine Answer - inhibit the cholinesterase enzyme and
increase the availability of Ach at the NMJ
what patients obtain less benefit from pyridostigmine Answer - patients with
anti-MuSK MG
how to reduce side effects of pyridostigmine Answer - lomotil or loperamide
MOA of glucocorticoids in MG Answer - anti-inflammatory,
immunosuppressive (inhibit T lymphocyte fxn), antiproliferative (inhibit DNA
synthesis)
mycophenolate mofetil MOA Answer - selective inhibition of purine synthesis
by the de novo pathway, inhibits proliferation of lymphocytes but not of other
cells
