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PSYCHOPHARMACOLOGY NUR660 REVIEW EXAM QUESTIONS WITH REVISED AND UPDATED ANSWERS

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PSYCHOPHARMACOLOGY NUR660 REVIEW EXAM QUESTIONS WITH REVISED AND UPDATED ANSWERS partial antagonist - Answer-Drug that acts as an agonist to some receptors, but an antagonist to others. Some opioid drugs have this property. Ligands - Answer-any molecule that binds specifically to a receptor ...

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  • September 28, 2024
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PSYCHOPHARMACOLOGY NUR660
REVIEW EXAM QUESTIONS WITH
REVISED AND UPDATED ANSWERS

partial antagonist - Answer-Drug that acts as an agonist to some receptors, but an
antagonist to others. Some opioid drugs have this property.

Ligands - Answer-any molecule that binds specifically to a receptor site of another
molecule

null ligands - Answer-non drugs

Biovailability - Answer-The concentration of drug present in the blood that is free to bind
to specific target sites

Pharmacokinetics - Answer-The process by which drugs are absorbed, distributed
within the body, metabolized, and excreted.

Pharmcodynamics - Answer-study of how the drug affects the body

first pass metabolism - Answer-Phenomenon in which the liver metabolizes some of a
drug before it can circulate through the body, particularly when the drug has been taken
orally.

second pass metabolism - Answer-Detoxifying synthetic reactions that require the
combination called conjugation reactions of the drug with small molecule such as
glucoronide, sulfate, or methyl groups.

Drugs not biotransformed - Answer-benzylepenicillin, aminoglycosides, metformin,
tubocurarine, amantadine

Norepinephrine - Answer-A catecholamine hormone the natural form of which is D,
although the L form has some activity; the base is considered to be the postganglionic
adrenergic mediator, acting on α and β receptors; it is stored in chromaffin granules in
the adrenal medulla in much smaller amounts than epinephrine and secreted in
response to hypotension and physical stress; in contrast to epinephrine it has little effect
on bronchial smooth muscle, metabolic processes, and cardiac output, but has strong
vasoconstrictive effects and is used pharmacologically as a vasopressor, primarily as
the bitartrate salt.

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