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Acetylsalicylic Acid (Aspirin) Questions and Answers

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Acetylsalicylic Acid (Aspirin) Questions and Answers overview of the experiment using salicylic acid and acetic anhydride to make acetylsalicylic acid (aspirin) salicylic acid starting material Previous Play Next Rewind 10 seconds Move forward 10 seconds Unmute 0:00 / 0:1...

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  • September 28, 2024
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Acetylsalicylic Acid (Aspirin) Questions
and Answers
overview of the experiment - answer using salicylic acid and acetic anhydride to
make acetylsalicylic acid (aspirin)

salicylic acid - answer starting material

acetic anhydride - answer starting material

acetylsalicylic acid - answer end product - aspirin

what kind of acid is used to protonate an O in acetic anhydride - answer phosphoric
acid

or

sulfuric acid, H3PO4
H-O-SO3H

also acts a catalyst!

what kind of reaction is this - answer exothermic

why do we add water during the reaction and not at the begining - answer if added at
the beginning it would hydrolyze the acetic anhydride and then the reaction could not
occur
^reason why we dont use HCl (80% water) and use sulfuric acid instead

add it in the middle to decompose extra acetic anhydride

**also its the crystallization solvent

hydrochloric acid is about as strong as sulfuric acid. why would HCl not be a satisfactory
catalyst in this reaction - answer HCl: 80% H2O, 20% HCl
sulfuric acid: 100% H2SO4

would hydrolyze the acetic anhydride, the reaction could occur

how do you account for the smell of vinegar when an old bottle of aspirin is opened -
answer moisture from the air will hydroyze the aspirin and break it down into salicylic
acid and acetic acid which is found in vinegar

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