NURS 8022 Exam 2 Studyguide transformed into flashcards
Questions With Complete Solutions
1. Apoferritin
2. Hemosiderin Correct Answer 1. Ferritin without attached
iron - (precursor to ferritin)
2. Ferritin micelles (very small cells) - the storage form of
ferritin ▪ Normal in small amounts in spleen, liver, bone marrow
▪ Can be pathophysiological in large amounts (lung,
subcutaneous tissue)
1. Endotoxin vs. 2. Exotoxin Correct Answer 1. Contained in
the cell walls of gram-negative bacteria and released during lysis
of bacteria
-- Pyrogenic bacteria: activate inflammation and produce fever
2. Enzymes released during growth
-- Damages cell membranes, activates second messengers,
inhibits protein synthesis
Active bone marrow sites Correct Answer pelvic bones
vertebrae
cranium
mandible
sternum
ribs
humerus
femur
,Active Immunity vs Passive Immunity Correct Answer Natural
exposure to foreign antigens (i.e immunization); slow onset,
long-lived
Passive: preformed antibodies from another host (i.e maternal
antibodies passed through placenta to fetus); rapid onset, short-
lived
Adaptive Immunity
- Third line of defense Correct Answer More
sophisticated/specific, less players, inducible, slower
Destruction of infectious microorganisms that are resistant to
inflammation
Long-term highly effective protection against future exposure to
the same microorganisms
** Bone marrow can distinguish between IDA and ACD **
Anisocytosis
Poikilocytosis Correct Answer Variation in RBC size
Variation in RBC shape
, Anthrax Correct Answer Bioweapon
Microorganism responsible: gram + spore-forming aerobic rod
Bacillus anthracis
CM: Prodromal symptoms then brief period of improvement
followed by rapid onset of high fever, severe respiratory
distress, shock and death within 24-36 hours
Aplastic Anemia Correct Answer Type of Normocytic-
Normochromic Anemias
Red bone marrow is replaced with fat; results in pancytopenia
because there are less hematopoietic cells
Most often caused by autoimmune
S&S: hypoxemia, pallor, weakness, dyspnea, fever
Diagnose via bone marrow biopsy
B Cells Correct Answer • Made in bone marrow; activated B
cells create plasma cells which turn into antibodies
• Responsible for humoral immunity that is mediated by
circulating antibodies
• Antibodies bind to antigens on bacteria and viruses
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