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CDCES EXAM STUDY GUIDE
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CDCES EXAM STUDY GUIDE...
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CDCES EXAM STUDY GUIDEFiasp (insulin aspart) - ANSWEROnset 2.5 minutes; peak 60 minutes; duration
3-5 hours.
ANSWER: Aspart (Novolog), lispro (humalog), and glulisine (apidra).Onset 5-
15 min; peak 30-90 min; duration <5 hours.
Regular insulin bolus - ANSWEROnset 30-60 minutes; peak 2-3 hours;
duration 5-8 hours
NPH insulin - ANSWEROnset: 2-4 hours; peak: 4-10 hours; duration: 10-16
hours.
Detemir (Levemir) - ANSWEROnset 3-8 hours; no peak; duration 6-24 hours
Glargine (Lantus/Basaglar) - AnswerOnset 2-4 hours, no peak, lasts 20-24
hours.
Degludec (Tresiba) - ANSWEROnset 1 hour; no peak; duration <42 hours.
NPH mix with regular (70/3" or 50/50) - ANSWEROnset 30-60 min; dual peak;
duration 10-16 hours
Novolog/Humalog or Ryzodeg combination (70/30, 75/25, and 50/50) –
ANSWEROnset 5-15 minutes; dual peak; lasting 24 hours.
, GLP-1 receptor agonist action - ANSWERIncretin mimetics boost insulin
release, decrease stomach emptying, promote satiety, suppress glucagon, lessen
the risk of CV mortality, MI, and stroke, and lower A1C.5–1.6, 1.6–6 kg weight
decrease
GLP-1 agonist names - ANSWER.Exabatide (Byetta), exanitide XR
(Bydureon), lieaglutide (Victoza), dulaglutide (Trulicity), lixisenatide
(Adlyxin), semaglutide (Ozempic), rybelsus
GLP-1 agonist side effects - ANSWERNausea, vomiting, weight loss, injection
site reaction, pancreatitis (abdominal pain and vomiting); avoid liraglutide,
dulaglutide, and liraglutide if family history of thyroid tumour
Amylin Mimetics (Pramlintide/Symlin) - AnswersLows stomach emptying,
suppresses glucagon; adverse effects - severe hypoglycemia risk, decrease
insulin upon starting, sickness, weight loss (lowers A1C.5-1).
Ideglira (autopsy) - ANSWERCombines degludec (ideg or tresiba) + liraglutide
(Victoza); daily injection 10-50 units; begin at 16 and titrate by 2 units.
Iglarlixi (soliqua): ANSWERGlargine (lantus) + lixisenatide (adlyxin)-glp; once
daily injection 1 hour before the first meal ranges from 15 to 60 units.
Biguanides (Metformin) - ANSWERDecreases hepatic glucose production and
increases insulin sensitivity; decreases cholesterol; no hypoglycemia or weight
gain; lowers 1-2%
Sulfonylureas - ANSWERGlyburide (Diabeta); glipizide (glucotrol);
glimepiride (amaryl); increase prolonged insulin release; may cause
hypoglycemia (most probable glyburide) and weight gain; decreases 1-2%
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