Psychopharmacology; Practice Study Guide Questions with Distinction level Marking scheme version 2024/2025
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Course
Psychopharmacology
Institution
Psychopharmacology
Psychopharmacology; Practice Study Guide Questions with Distinction level Marking scheme version 2024/2025
How is action of ach inactivated? - correct answer Acetylcholinesterase (ache)
Name an agonist and antagonist for nicotinic and muscarinic ach receptors. - correct answer
Nicotine Agon...
Psychopharmacology; Practice Study
Guide Questions with Distinction level
Marking scheme version 2024/2025
How is action of ach inactivated? - correct answer Acetylcholinesterase (ache)
Name an agonist and antagonist for nicotinic and muscarinic ach receptors. - correct
answer
Nicotine Agonist nicotinic receptor
D-tubocurarine
Antagonist nicotinic receptor
Muscarine Agonist
Atropine Antagonist
Briefly describe distribution of ach in the brain - correct answer Rephe nuclei
Vestibular nuclei
Deep cerebellar nuclei
Locus coeruleus
Lateral hypothamus
Substantia Nigra
Thalamus
Amygdala
Olfactory Bulb
Neo-cortex
Hippocampus
What behavioral effects does ach mediate - correct answer When low→ Muscle
contraction
, When high→ inhibits muscular contraction
PNS/CNS
Heart rate; bronchioles secretion of mucus in the respiratory tract;
Intestinal
Salvia
Sweat
Tears;
Can also be seen in the pupils
Describe the variety of glutamate receptors. How do they work? - correct answer
Ionotropic
AMPA
Kainite
NMDA needs Glycine, and 2 glutamate
And its dependant on AMPA to get depolarized to get ride of Mg2+
Requires binding of two glutamate molecules
Primary excitatory NT
Metabotropic glutamate receptors
Inhibit camp or activate phosphoinositide second-messenger system
May act as autoreceptors
Mglur1-mglur8
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