Intravenous Lasix is given slowly over ___ minutes - Answer 1-2
which class of diuretics may be administered to offset the potassium depleting action of
the loop diuretics - Answer aldosterone blockers (potassium sparing) such as
spironolactone
describe the MOA of thiazide diuretics - Answer block reabsorption of sodium and
chloride in the distal convulated tubule
describe the MOA of spironolactone Answer blocks aldosterone in distal nephron,
potassium is retained, sodium excreted
describe the MOA of furosemide (Lasix) Answer blocks reabsorption of sodium and
chloride in the ascending loop of henle
why are ace inhibitors and potassium-sparing diuretics problematic Answer both can
lead to hyperkalemia
What is the major indication for using a potassium-sparing diuretic such as
spironolactone (Aldactone) -Answer common use-to counteract loss of potassium when
loop or thiazide diuretic used
What are the clinical manifestations of electrolyte imbalance -Answer confusion, muscle
twitching, weakness, irregular pulse, and nausea
When the baroreceptor reflex is activated in response to low blood pressure, the
arterioles ___ and the heart rate ____ -Answer constrict, increases
Name causes of hypokalemia Answer decreased intake, diuretics, excessive sweating,
increased insulin, alkalosis
, Name the side effects of furosemide (lasix) Answer depletes electrolytes sodium,
chloride, potassiu, hypotension, dehydration
What time of day is most optimal to give a diuretic? Answer early morning
What antibiotic when given with furosemide (lasix) can potentiate hearing loss? Answer
gentamycin, (aminoglycoside antibiotic)
dehydration from the use of diuretics can encourage thromboembolism. describe the
signs and symptoms of thromboembolism - Answer headache, pain in chest calves or
pelvis, positive homan's sign, erythema
what are the signs and symptoms of ototoxicity? - Answer impairment of hearing, ringing
in the ears, and vertigo
what is the significant adverse effects of spironolactone? - Answer hyperkalemia,
menstrual irregularities, hirsutism, lowering of voice, and gynecomastia in men
when venous return increases, does cardiac output increase or decrease - Answer
increase
does HTN increase or decrease afterload Answer increase
how is intravenous lasix administered Answer IV push over 2 minutes
what class of diuretics is especially useful in patients with renal impairment Answer loop
diuretics
what is the potential problem when diuretics and digoxin are used together Answer low
potassium can increase digoxin levels to toxic range
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