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Exam 4: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Review |Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville
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NURS 615/ NURS615
Exam 4: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Review |Qs & As| 100% Correct| Grade A (Verified Answers)
Q: How does metformin work?
Answer:
Decreases hyperglycemia by decreasing hepatic glucose production called hepatic gluconeogenesis. The average pe...
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1. Exam (elaborations) - Exam 4: nurs 615/ nurs615 (latest 2024/ 2025 update) advanced pharmacotherapeutics re...
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1. Exam (elaborations) - Exam 4: nurs 615/ nurs615 (latest 2024/ 2025 update) advanced pharmacotherapeutics re...
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3. Exam (elaborations) - Exam 3: nurs 615/ nurs615 (latest 2024/ 2025 update) advanced pharmacotherapeutics re...
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1. Exam (elaborations) - Exam 4: nurs 615/ nurs615 (latest 2024/ 2025 update) advanced pharmacotherapeutics re...
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5. Exam (elaborations) - Exam 2: nurs 615/ nurs615 (latest 2024/ 2025 update) advanced pharmacotherapeutics co...
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ExamI4:INURSI615/INURS615I(LatestI2024
/I2025IUpdate)IAdvancedI
PharmacotherapeuticsIReviewI|QsI&IAs|I
100%ICorrect|IGradeIAI(VerifiedIAnswers)
Q:IHowIdoesImetforminIwork?
Answer:
DecreasesIhyperglycemiaIbyIdecreasingIhepaticIglucoseIproductionIcalledIhepaticIgluconeogen
esis.ITheIaverageIpersonIwithItypeI2IdiabetesIhasIthreeItimesItheIrateIofIgluconeogenesis,Imet
forminItreatmentIreducesIthisIbyIoverI1/3rd.ITheImolecularImechanismIofImetforminIisn'tIcom
pletelyIunderstood.IInIadditionItoIsuppressingIhepaticIglucoseIproduction,ImetforminIincreases
IinsulinIsensitivity,IenhancesIperipheralIglucoseIuptakeIbyIinducingItheIphosphorilizationIofIgl
u4IenhancerIfactor,IdecreasesIinsulinIinducedIsuppressionIofIfattyIacidIoxidation,IandIdecrease
sIabsorptionIofIglucoseIfromItheIGIItract.IAlsoIofInote**IMetforminIhelpsIreduceILDLIcholes
terolIandItriglycerideIlevelsIandIisInotIassociatedIwithIweightIgain,IinIsomeIpeopleIitIhelpsIpr
omoteIweightIloss**
Q:IWhatIdiagnosticItestingIisIrequiredIbeforeIandIthroughoutItherapyIwithImetformin?
Answer:
MetforminIisInotImetabolized,IitIisIclearedIfromItheIbodyIbyItubularIsecretionIandIisIsecretedI
unchangedIinItheIurine.IMetforminIisIundetectableIinIbloodIplasmaIwithinI24IhrsIofIaIsingleIo
ralIdoseItheIaverageIeliminationIhalf-
lifeIinIplasmaIisI6.2IhrsIasIitIisIsecretedIinItheIurineIyouIshouldIcheckIaIserumIcrtItoIassessIre
nalIfunction.
Q:IWhatIisItheIactionIofIgliptin?
Answer:
,TheImechanismIofIDDP-
4IinhibitorsIisItoIincreaseIincretinIlevelsIincretinIareIGLP1IandIGIPIwhichIinhibitIglucagonIrel
easeIinIwhichIinIturnIincreasesIinsulinIsecretion,IdecreasesIgastricIemptying,IandIdecreasesIblo
odIglucoseIlevels
Q:IHowIdoIGLPIagonistsIwork?
Answer:
TheyIbindIdirectlyItoIaIreceptorIinItheIpancreaticIbetaIcell.ITheseIagentsIworkIinItheIsameIpat
hwayIasItheIDPP-4IinhibitorsIasImentionedIaboveIbutIareIgenerallyIconsideredImoreIpotent.
Q:IWhenIshouldIexenatideIbeIadministered?
Answer:
60IminutesIpriorItoItheImorningIandIeveningImeal
Q:IHowIwillIyouIassessIforIgranulocytopenia?
Answer:
SignsIofIaIColdIorIfluIincludingIfeverIandIsoreIthroat
Q:IWhatIareItheIadverseIeffectsIofIpropylthiouracil?
Answer:
Agranulocytosis,Ithrombocytopenia,IandIfulminantIliverIfailureIasIstatedIabove,Ipt'sIonIPTUIw
henItheyIdevelopIfeverIorIsoreIthroat,IitIwouldIbeIimportantItoIcheckIaICBCIpreferablyIwithIa
IsmearIandIaIdiff.
, Q:IWhatIareItheIadverseIeffectsIofIlevothyroxine?
Answer:
TachycardiaIandIanginaIinItheIelderly
Q:IAIpatientIdevelopsIaItoxicIgoiter.IWhatIisItheIrecommendedItreatment?
Answer:
MethimazoleIforIoneImonthIthenIradioactiveIiodineI(p.I641)
Q:IWhatIareItheIadverseIeffectsIofIPTUIandImethimazole?
Answer:
PTU-IFatalIagranulocytopeniaIlookIforIfeverIandIsoreIthroatIandITEMPORARYIALOPECIA
Q:IWhatIisItheIactionIofIbiphosphonates?
Answer:
BoneIundergoesIconstantIturnoverIandIisIkeptIinIbalanceIbyIosteoblastsIcreatingIboneIandIoste
oclastsIdestroyingIbone.IBisphosphonatesIinhibitItheIdigestionIofIboneIbyIencouragingIosteocl
astsItoIundergoIapoptosisIorIcellIdeathIthereIbyIslowingIboneIloss.IOralIbisphosphonatesIcanIc
auseIupsetIstomachIandIinflammationIasIwellIasIerosion.IErosionsIofItheIesophagusIwhichIisIt
heImainIproblemIofIoralIandIcontainingIpreparations.IThisIcanIbeIpreventedIbyIsittingIuprightI
forI30-
60IminutesIafterItakingItheImedication.IIfItheIpatientIdoesIdevelopIsomeItypeIofIgastricIdistres
s,IgiveIthemIoralI30mlIofIMaaloxI3IhrsIafterItakingIit.IIVIbisphosphonatesIcanIgiveIfeverIandI
fluIlikeIsymptomsIafterItheIfirstIinfusionIwhichIisIthoughtItoIoccurIbecauseIofItheirIpotentialIt
oIactivateIhumanITIcells