MSN 570 Advance Patho Exam Questions With Verified Answers.
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Course
MSN 570
Institution
MSN 570
MSN 570 Advance Patho Exam Questions
With Verified Answers.
MI - answerDeath of myocardium from sudden blockage of coronary artery blood flow
What causes cell death in MI? - answerunstable plaque breaks off, triggering platelet
aggregation, coagulation cascade and thrombus formation. continued ...
MSN 570 Advance Patho Exam Questions
With Verified Answers.
MI - answer✔Death of myocardium from sudden blockage of coronary artery blood flow
What causes cell death in MI? - answer✔unstable plaque breaks off, triggering platelet
aggregation, coagulation cascade and thrombus formation. continued no blood flow in 10
seconds ischemia, 20 minutes cell die
What consequence of cell death leads to CP? - answer✔hypoxia as cannot meet cell demand for
oxygen
How is MI diagnosed - answer✔EKG (STEMI) or elevated Troponin (non-STEMI)
What might you find in blood consistent with MI? - answer✔elevated CK MB, Troponin
Where does CK MB and Troponin come from? - answer✔Release of lysosomal enzymes; CK
MB detected after myocardial necrosis, Troponin released from damaged heart muscle
3 mechanism of cell injury related to reperfussion injury - answer✔ischemia, necrosis,
reperfussion l/t RAS
define reperfussion injury - answer✔injury that occurs after oxygen is reintroduced to tissue
perfusion
how does inflammatory process contribute to reperfussion injury? - answer✔as oxygen is
reintroduced it comes in contact with damaged proteins triggering inflammatory response
how does oxidative process contribute to RI? - answer✔RAS causes impairment of cell
membrane and pro-apotptoic cells release. making cell unstable
what is primary Hypertension? - answer✔Essential or idiopathic, elevated BP without an
identified cause, accounts for 90 - 95% of all cases of hypertension?
what is secondary hypertension? - answer✔Elevated BP, labile BP; related to conditions ie
kidney dz; resistant to BP meds
what is significance of Ventricular hypertrophy and HTN? - answer✔persistent hypertension
leads to ventricular hypertrophy; decrease CO
what comorbidities/conditions does HTN cause? - answer✔stroke, ischemia, heart failure,
aneurysm, hemorrhage
what is preload? - answer✔volume of blood in ventricles at end of diastole
what is afterload? - answer✔peripheral resistance against which the left ventricle must pump
hoe does HTN l/t CHF? - answer✔overwork left ventricle due to increase pressure; decreased
pumping ability of heart and decreases CO.
identify pathological process of gangrene? - answer✔form of coagulative necrosis; interruption
of blood flow l/t denaturing cells enzymes and bacterial invasion
three types of gangrene - answer✔dry, wet & gas
what is the major treatment approach for gangrene? - answer✔removing affective tissue to
prevent infection; treating problem that led to gangrene
why use antibiotic for gangrene? - answer✔to slow bacterial damage
What are the two major necrotic processes? - answer✔Coagulative and liquifactive
What is coagulative necrosis? - answer✔necrosis caused y interruption of blood flow l/t desrease
Ph, and bacterial growth
what is liquifactive necrosis? - answer✔Caustic enzymes dissolve and liquify necrotic cell;
cottage cheese like appearance.
Describe dry gangrene - answer✔hypoxia l/t ischemia l/t last of blood flow l/t coagulative
necrosis
Describe wet gangrene - answer✔extensive damage from bacteria with WBC's that have
invaided site produces a liquid wound
describe gas gangrene - answer✔Presence of clostridium (aerobic bacteria) releases toxins and
destroy surrounding cell. Most fatal.
Colon cancer inherited vs genetic - answer✔Colon CA inherited- occurs on gremline
Colon CA genetic occurs on somatic cells
Describe FAP - familial adenomatous polyposis - answer✔Gene defect on chromosome 1 or 5;
involves tumor suppressor genes, hereditary condition
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