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SCSU NUR 343 Exam 1 with verified solutions
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SCSU NUR 343 Exam 1 with verified solutions
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SCSU NUR 343 Exam 1drug - correct answer ✔✔any chemical that can affect living processes
pharmacology - correct answer ✔✔the study of drugs and their interactions with living systems
clinical pharmacology - correct answer ✔✔study of drugs in humans
therapeutics - correct answer ✔✔The use of drugs to diagnose, prevent, or treat disease or to prevent
pregnancy *or* the medical use of drugs
The Big Three - correct answer ✔✔properties of an ideal drug
-effectiveness
-safety
-selectivity
therapeutic objective - correct answer ✔✔achieving the maximum benefit with minimal harm
pharmacokinetics - correct answer ✔✔the impact of the body on drugs
pharmacodynamics - correct answer ✔✔the impact of the drug on the body
5 rights of medical administration - correct answer ✔✔patient, dose, drug, time, route
Food Drug Cosmetic Act - correct answer ✔✔1938 - required all new drugs be reviewed by the
government before being released to the public
Controlled Substances Act - correct answer ✔✔1970 - set rules for marketing and distributing of meds
that can be addictive and classified them by schedule (narcotics)
,what is NIOSH/what do they do? - correct answer ✔✔National Institute for Occupational Safety and
Health
-promotes occupational safety
-IDs hazardous materials
-literature and training
phases of new drug development - correct answer ✔✔Phase I - concept, chemical property, healthy
volunteers
Phase 2/3 - therapeutic effects, dose range, safety, effectiveness
Phase 4 - safe, risk vs benefit, released to general population under observation
OTC drugs are ___ percent of administered drugs - correct answer ✔✔60
physiologic adaptation - correct answer ✔✔adaptation due to normal body process
atrophy - correct answer ✔✔decrease in cell size
hypertrophy - correct answer ✔✔increase in cell size
hyperplasia - correct answer ✔✔increase in number of cells
dysplasia - correct answer ✔✔deranged cellular growth
metaplasia - correct answer ✔✔replacement of one type of cell with another due to chronic injury or
irritation
cellular injury - correct answer ✔✔cell unable to maintain homeostasis
most common cause of cellular injury - correct answer ✔✔hypoxia
, hypoxia results from - correct answer ✔✔-lack of oxygen
-loss of hemoglobin
-decreased RBC production
-respiratory and CV system diseases
-poisoning of oxidative enzymes
most common result of hypoxia - correct answer ✔✔ischemia (extremely painful oxygen deficiency)
ischemia-reperfusion injury - correct answer ✔✔-caused by restoration of blood flow and oxygen
-mechanisms: oxidative stress, inflammation, complement activation, increased intracellular calcium
anoxia - correct answer ✔✔absence of oxygen
cellular responses to ischemia - correct answer ✔✔decrease in ATP, failure of Na/K pump and Na/C
exchange, cellular swelling, hydropic change
mechanism of injury - correct answer ✔✔a situation in which the injury occurs
free radicals can damage - correct answer ✔✔lipid peroxidation, alteration of proteins/DNA,
mitochondria
chemical injury - correct answer ✔✔cellular injury followed by exposure to xenobiotics
xenobiotics - correct answer ✔✔substances that are foreign to the body
leading cause of child poisoning - correct answer ✔✔chemical injury
blunt force injuries - correct answer ✔✔result of mechanical force to body (contusions, lacerations,
fractures)
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