ONS Chemotherapy Immunotherapy Certificate Exam Questions With Verified Answers
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Course
ONS Chemotherapy Immunotherapy
Institution
ONS Chemotherapy Immunotherapy
ONS Chemotherapy Immunotherapy
Certificate Exam Questions With Verified
Answers
Define neoadjuvant therapy - answerTreatment is given prior to surgery to shrink the tumor
Define adjuvant therapy - answerAdditional cancer treatment given after the primary treatment
to lower the risk that the ca...
ONS Chemotherapy Immunotherapy
Certificate Exam Questions With Verified
Answers
Define neoadjuvant therapy - answer✔Treatment is given prior to surgery to shrink the tumor
Define adjuvant therapy - answer✔Additional cancer treatment given after the primary treatment
to lower the risk that the cancer reoccur
3 subcategories of alkylating agents: - answer✔1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed alkylating agents as they
work similarly)
3. Nitrosoureas
Common alkylating agents: - answer✔Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: - answer✔Cisplatin (Platinol)
Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? - answer✔Able to cross the blood-brain barrier; can
be effective in treating some brain tumors
Common nitrosoureas agents: - answer✔Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: - answer✔Carboplatin
These agents are typically categorized as highly emetogenic: - answer✔1. Alkylating agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas: - answer✔BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? - answer✔Bladder protectant with administration of
cyclophosphamide or ifosfamide
Instruct pts receiving ________ to avoid exposure to cold air and consuming cold fluids for 3-4
days following treatment - answer✔Oxaliplatin
How do antimetabolites function? - answer✔By blocking DNA and RNA growth by interfering
with enzymes needed for normal cell metabolism
Antimetabolites work in the ___ phase. - answer✔S
Common side effects of antimetabolites: - answer✔Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: - answer✔Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what route of administration for
vincristine? - answer✔IV piggyback via gravity
Anthracycline antitumor abx work by: - answer✔Interfering with enzymes necessary for DNA to
replicate in ALL phases of the cell cycle
The two major classifications of antitumor antibiotics are: - answer✔Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: - answer✔Daunorubicin
Doxorubicin
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