Exam (elaborations)
BIOL 302 Exam 1 Questions and Answers (Graded A)
BIOL 302 Exam 1 Questions and Answers
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BIOL 302 Exam 1 Questions and
Answers
How iimany iidifferent iiamino iiacids iiare iiused iiin iimaking iiproteins? ii- iiAnswers ii-20
In iia iifolded iiprotein, iimost iiof iithe iinonpolar iiamino iiacids iiare iiburied iiinside iithe iiprotein
iifold, iiwhereas iithe iipolar iiand iicharged iiside iichains iiare iiexposed iito iithe iicomponents
iiin iithe iicytosol. iiThis iifold iiis iimore iistable iibecause iiof iithe iiexpulsion iiof iinonpolar
iiatoms iifrom iicontact iiwith iiwater, iifavoring iithe iiinteraction iiof iinonpolar iiatoms iiwith
iieach iiother. iiWhat iiis iithe iitype iiof iinoncovalent iiinteraction iicalled? ii- iiAnswers ii-
hydrophobic iiinteraction
Which iiof iithe iifollowing iiis iinot iia iifeature iicommonly iiobserved iiin iiBeta iisheets? ii-
iiAnswers ii-coiled-coil iipatterns
Why iiare iialpha iihelices iiand iiBeta iisheets iicommon iifolding iipatterns iiin iipolypeptides?
ii- iiAnswers ii-amino iiacid iiside iichains iiare iinot iiinvolved iiin iitheir iiformation
What iidoes iithe iiprimary iistructure iiof iia iiprotein iirefer iito? ii- iiAnswers ii-the iiamino iiacid
iisequence iiof iithe iiprotein
Protein iimolecules iithat iihave iia iiquaternary iistructure iihave ii- iiAnswers ii-two iior iimore
iipolypeptide iichains
The iispecialized iiDNA iisequences iithat iicap iithe iiends iiof iieukaryotic iichromosomes iiare
iicalled: ii- iiAnswers ii-telomeres
The iiDNA iiin iieukaryotic iichromosomes iiis iifolded iiinto iia iicompact iiform iiby iiinteractions
iiwith: ii- iiAnswers ii-proteins
What iistatement iiabout iinucleosomes iiis iifalse? ii- iiAnswers ii-nucleosomes iiare iifound
iionly iiin iimitotic iichromosomes
T/F: iiIn iithe iichromatin iiof iiinterphase iichromosomes, iiregions iiof iithe iichromosome iithat
iicontain iigenes iibeing iiexpressed iiare iigenerally iimore iicompact, iiwhile iithose iithat
iicontain iinonexpressed iigenes iiare iimore iigenerally iimore iiextended. ii- iiAnswers ii-false
, Nucleosomes iirepresent iithe iifirst iiand iimost iifundamental iilevel iiof iichromatin iipacking.
iiWhich iistatement iiis iitrue iiabout iithe iiassociation iiof iihistone iiproteins iiand iiDNA? ii-
iiAnswers ii-histone iiproteins iihave iia iihigh iiproportion iiof iipositively iicharged iiamino
iiacids, iiwhich iibind iitightly iito iithe iinegatively iicharged iiDNA iibackbone
T/F: iiHistones iiare iian iiexample iiof iia iisequence-specific iiDNA-binding iiprotein ii-
iiAnswers ii-False
How iido iichromatin-remodeling iicomplexes iiwork? ii- iiAnswers ii-they iiuse iithe iienergy
iifrom iiATP iihydrolysis iito iialter iithe iiarrangement iiof iinucleosomes, iirendering iicertain
iiregions iiof iithe iiDNA iimore iiaccessible iito iiother iiproteins
The iitails iiof iithe iicore iihistone iiproteins iican iibe iichemically iimodified iiby iithe iicovalent
iiaddition iiof iiwhat iitype iiof iichemical iigroup? ii- iiAnswers ii-All iiof iithe iiabove ii(Acetyl,
iiMethyl, iiPhosphate)
In iia iiDNA iidouble iihelix, iiwhich iistrand iiwill iiserve iias iithe iitemplate iiduring
iitranscription? ii- iiAnswers ii-The iistrand iithat iiruns iiin iithe ii3'-to-5' iidirection
The iioctameric iihistone iicore iiis iicomposed iiof iifour iidifferent iihistone iiproteins. iiOnce
iithe iicore iioctamer iihas iibeen iiformed, iiDNA iiwraps iiaround iiit iito iiform iia iinucleosome
iicore iiparticle. iiWhich iiof iithe iifollowing iihistone iiproteins iidoes iinot iiform iipart iiof iithe
iioctameric iicore? ii- iiAnswers ii-H1
The iiprocess iiof iiDNA iireplication iirequires iithat iieach iiof iithe iiparental iiDNA iistrands iibe
iiused iias iia ii_______ iito iiproduce iia iicomplementary iinew iistrand ii- iiAnswers ii-template
The iistructures iiof iithe iifour iibases iiin iiDNA iiare iigiven iiin iiFigure ii3. ii
(a) iiWhich iiare iipurines iiand iiwhich iiare iipyridines? ii
(b) iiWhich iibases iipair iiwith iieach iiother iiin iidouble-stranded iiDNA? ii- iiAnswers ii-(a)
iipurines- iiA iiand iiG ii
pyrimidines- iiC iiand iiT ii
(b) iiA/T iiand iiC/G
Although iiall iiprotein iistructure iiare iiunique, iithere iiare iicommon iistructural iibuilding
iiblocks iithat iiare iireferred iito iias iiregular iisecondary iistructures. iiSome iihave iialpha
iihelices, iisome iihave iiBeta iisheets, iiand iistill iiothers iihave iia iicombination iiof iiboth.
iiWhat iimakes iiit iipossible iito iihave iithese iicommon iistructural iielements? ii- iiAnswers ii-
hydrogen iibonds iialong iithe iiprotein iibackbone
The iicorrect iifolding iiof iiproteins iiis iinecessary iito iimaintain iihealthy iicells iiand iitissues.
iiUnfolded iiproteins iiare iiresponsible iifor iisuch iineurodegenerative iidisorders iias
iiAlzheimer's, iiHuntington's, iiand iiCreutzfeld-Jacob iidisease ii(the iispecific iifaulty iiprotein
iiis iidifferent iifor iieach iidisease). iiWhat iiis iithe iiultimate iifate iiof iithese iidisease-causing,
iiunfolded iiproteins? ii- iiAnswers ii-They iiform iiprotein iiaggregates iicalled iiamyloid iifibrils.