Pathology exam 1 2024 questions & answers
The most important role for the mitochondria in the cell: SUMMER '15 SPRING '15 SPRING '14
a. Production of ATP
b. Protect labile proteins
c. Remove defective cell parts
d. Identify paternity - ANSWERSProduction of ATP
Loss of ATP generating c...
Pathology exam 1 2024 questions &
answers
The most important role for the mitochondria in the cell: SUMMER '15 SPRING '15 SPRING '14
a. Production of ATP
b. Protect labile proteins
c. Remove defective cell parts
d. Identify paternity - ANSWERSProduction of ATP
Loss of ATP generating capacity by mitochondria results in
a. Increased glycolysis
b. Decreased protein synthesis
c. Loss of ionic and osmotic gradients
d. All of the above - ANSWERSAll of the above
Reperfusion injury is associated with
a. The production of free radicals
b. Augmented inflammatory cell infiltration
c. Depleted free radical scavenging capacity
d. All of the above - ANSWERSAll of the above
Alteration of cellular organelles may indicate
a. An adaptive response
b. A chronic reversible injury
c. An irreversible injury
d. All of the above - ANSWERSAll of the above
The accumulation of non-digestible substances in phagocytic cells occurs with the formation of
,a. Hemosiderin granules
b. Lipofuschin granules
c. Tattoos
d. All of the above - ANSWERSAll of the above
Apoptosis
a. Always incites an inflammatory response
b. Always pathologic
c. A normal part of development
d. Only occurs with overwhelming cell injury - ANSWERSA normal part of development
Apoptosis is associated with
a. Indiscriminate destruction of genetic material
b. Specific dismantling of chromosomes
c. Membrane destruction with leakage of intracellular contents
d. Extra-cellular release of lysosomal enzymes - ANSWERSSpecific dismantling of chromosomes
Apoptosis is seen in areas of
a. Tissue degeneration
b. Ischemic tissue injury
c. Embryonic developments
d. All of the above - ANSWERSAll of the above
Dystrophic calcification requires:
a. Normal calcium metabolism and abnormal tissue
b. Abnormal calcium metabolism and normal tissue
c. Never impairs function
d. Only occurs in the presence of cancer - ANSWERSNormal calcium metabolism and abnormal tissue
,Metastatic calcification occurs:
a. With parathyroid necrosis
b. Liver failure
c. Renal failure
d. All of the above - ANSWERSRenal failure
Aging involves
a. An increase in telomere length
b. Increased telomere activity
c. A decrease in telomere length
d. The efficient elimination of damaged organelles - ANSWERSA decrease in telomere length
The cell identified as the main character in acute inflammation is:
a. The lymphocyte
b. Fibroblast
c. The PMN
d. The macrophage - ANSWERSThe PMN
The hallmark of acute inflammation in PMN cell emigration and:
a. Increased vascular permeability
b. Impaired vasodilatation
c. Increased plasma oncotic pressure
d. Slow response to foreign substances - ANSWERSIncreased vascular permeability
Which of these areas of the body would be the least likely to be able to generate health inflammatory
response:
a. Lung tissue
b. Dermis
c. Ischemic tissue
, d. Myocardium - ANSWERSIschemic tissue
The area of the vasculature most associated with WBC emigration is the
a. Capillary
b. Meta-arteriole
c. Post-capillary venule
d. Arteriole - ANSWERSPost-capillary venule
Stasis of flow associated with the local decreases in intravascular volume plays an important role in:
a. WBC adhesion to endothelial cells
b. Decreased oxygen deliver to affected tissues
c. Impaired red cell deformability
d. Reactive hyperemia - ANSWERSWBC adhesion to endothelial cells
Inflamed capillaries become porous because of:
a. Direct endothelial injury
b. WBC released mediators
c. Increased transcytosis
d. All of the above - ANSWERSAll of the above
One of the initial responses in acute inflammation is endothelial expression of
a. Surface selectins
b. Surface integrins
c. Proliferation factors
d. Apoptotic molecules - ANSWERSSurface selectins
What is the correct sequence of events in WBC emigration:
a. Endothelial cell activation --> WBC rolling -->stable adhesion -->WBC transmigration
b. Stable adhesion -->WBC rolling --> Transmigration -->endothelial activation
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