All states have title protections for NPs - ANSWER True
Who regulates NP practice - ANSWER The board of nursing
In addition to the board of nursing, who else regulates NP practice - ANSWER 5
states have joint oversight with the Medical Board
The scope of practice for NPs is determined by what - ANSWER The NP license
Investigational New Drug (IND) - ANSWER Required before an investigational drug
or biological product can be administered to humans
What is the IND application - ANSWER A compilation of all known information about
the compound
Other than the information about the compound what does the IND application
include - ANSWER Description of the clinical research plan for the product
Specific protocol for phase I study
ADRs of NSAIDs - ANSWER GI bleed
Kidney damage
ADRs of opioids - ANSWER Constipation
Respiratory depression
Hypotension
ADRs of ASA - ANSWER Tinnitus
Bleeding
Opioids interact with what kind of receptors - ANSWER Mu
Kappa
Delta
Sigma
What is the diagnostic duration of time for acute pain - ANSWER Less than 6 months
,Acute somatic pain comes from - ANSWER Connective tissue
Muscle
Bone
Skin
Acute visceral pain arises from - ANSWER The internal organs and abdomen
Referred pain - ANSWER Pain that is present in an area distant from its point of
origin
All opioids are rated against what - ANSWER Morphine
Which opioid is a prototype - ANSWER Morphine
Single agent product opioids - ANSWER Oxycodone
Morphine
Combination product opioids - ANSWER Vicodin
Percocet
Percodan
Tylenol with codiene
Opioid pharmacodynamics - ANSWER Bind to opioid receptors in the CNS
Opioid pharmacokinetics - ANSWER Vary
Opioid ADRs - ANSWER CNS sedation
Constipation
Euphoria
Cluster HA rational drug selection - ANSWER Oxygen 100% for 15-30 minutes
Suppositories or intranasal or IM DHE
Intranasal lidocaine
Sumatriptan
Things to watch with ginseng - ANSWER Potentiates insulin
, Things to watch with melatonin - ANSWER Monitor when patients are on
benzodiazepines, narcotics, and anti-depressants
Things to watch with St. John's Wort - ANSWER SSRIs
SNRIs
Pharmacodynamics of SSRIs - ANSWER All SSRIs have selective inhibitory effects
on presynaptic serotonin reuptake
SSRI absorption - ANSWER Slow absorption
SSRI half life - ANSWER 26 hours
SSRI metabolism - ANSWER Extensive first pass metabolism
Fluoxetine half life - ANSWER 1-3 days
Fluoxetine first metabolite - ANSWER 4-16 days
When metabolizing SSRIs what enzymes might be involved - ANSWER CYPC19
CYP2D6
Uses for beta blockers - ANSWER Post-MI antidysrhythmias
Migraine prophylaxis
Arrhythmias
Adjustment in doses with renal impairment
Role of cranberry for UTIs - ANSWER May exert a bacteriostatic effect by inhibiting
the adherence of organisms to bladder mucosa
Antibiotics used to treat UTIs - ANSWER Trimethoprim/sulfamethoxazole
(TMP/SMZ),
Nitrofurantoin,
Fluoroquinolones,
Cephalosporins
Penicillins
What medication is used as a urinary analgesic - ANSWER Phenazopyridine
Treatment for pernicious anemia - ANSWER Initial dose 1,000 mcg/day IM or SC for
7 days
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