Naplex Important Questions And Answers
Rated A+ 2024-2025.
onsets for laxatives - correct answer. Fast :
1-osmotics oral: 30minutes to 96 hrs :
2-Osmotics rectal :15-30 minutes (Glycerin)
3-Emollient rectal : 2-15 minutes like docesate
4-Lubricant rectal : 2-15 minutes
Rest of the orals are above 6 hrs...
H.pylori treatment - correct answer. All therapy are for up to 14 days.
First line QUAD: Pepto + flagyl + tetracycline + PPI (Tetrtra Flag PPPP)
then : clarith + flagyl + PPI
Triple: clarith + amox + PPI only use is clarith resitance <15% and no Macrolide before.
levo + amox + PPI
PI-BI-MET-TET
CAMP
CAP
If you get an Amiodarone Case in the exam, please watch for the following: - correct
answer. >>>>>Look if patients in the case receive or suffer any of :
1-Digoxin and statin or warfarin (should reduce doses / Digo by 50% and statins limits)
2-Iodine sensitivity
3-No Heparin in same line.
4-pulmonary / liver ^LFTs / Thyroid
,5-Sever sinus node disfunction unless patient has an artificial one)
6-Look for any drug that cause QT^ or reduce HR.
>>>>Look on the process of infusion:
1-Non PVC , Need filter / slow infusion to avoid bradycardia
2-drug of choice in HF as antiarrythmic ( plus Dofelitide)
3-Always in hospital for loading
Last issue : BLUE SKIN
Lab test for liver - correct answer. AST / ALT elevated / Albumin low / Tbili and
Amonia
What is CK lab test? - correct answer. Creatinine Kinase to assess muscle damage or
inflamation. Drugs could increase CK like Statin and fibrates, tenovir (Hep B and
HIV)and raltegravir and dolutegravir , daptomycin
Drugs that effect Thyroxine? - correct answer. Amiodarone and interferon (Up and
dawn) / Lithium and (Oxy) carbamazepine decrease to mean hypothyrism
Thyroxine lab reult test trap - correct answer. When TSH is elevated , it means HYPO
and NOT hyper.
Drugs that raise Uric acid blood level - correct answer. Diuretics , Niacin,
pyrazinamide (TB treatment) and high dose Aspirin,
Thyroxine lab result test trap - correct answer. When TSH is elevated , it means
HYPO and NOT hyper.
Drugs that can cause SJS or Ten - correct answer. Penicillin Phenytoin piroxicam (3P
for SJS & Ten) Allopurinol, Sulfamethoxazole, Lamotrigine. carbamazepine
Drugs that can induce Lupus - correct answer. -Procainamide -anti arythmic
-Hydralazine - anti histamine
-INH - TB treatment
-Chlorpromazine -Anti pschotic
-Methyldopa
- Anti TNF agent
-quinidine (Malaria and arrhythmia)
- Terbinafine (Anti fungal)
-Minocycline (antibiotic)
Mneumonic SHIPP (Salazopirin, Hydralazin,INZ,Phytoin,Procainamide) Hydra and
Procain are highest.
Drugs that can cause lactic acidosis - correct answer. NRTIs and Metformine
Drugs that are contraindicated in HF? - correct answer. 1-NSAIDs
2-Non pyridine CCBs specially verapamil
3- C.steroids
4-some anti arrythmia drug like Flecainide and dronedarone
5-TCA , Thiazolidinediones(e.g. rosiglitazone, pioglitazone),
6-Anti cancer :Anthracyclines (doxorubicin,daunorubicin), cyclophosphamide,
trastuzumab (Herceptin), tyrosine kinase inhibitors
(e.g. sunitinib) may cause heart failure4
, 7-Closapine.
8-Decongestants for coughs and colds such as pseudoephedrine may
increase workload on the heart .
Drugs cannot be infused using PVC-DEHP container - correct answer. LATIN
L:Lorazepam
A:Amiodarone
T:Tacrolimus
I: Insulin
N: Nitoglycerin
Drugs infused only using Saline IV bags - correct answer. DEAP CIA
D: Daptomycin (cubicin)
E: Ertapenem ( Invanz)
A: Ampicillin/sulbactam ( Unasyn)
P: Phenytoin (Dilantin)
Antibiotics for CRE pathogen? - correct answer. Polymyxin
Avycaz (cefazidime/avibactam)
Antibiotic for ESDLs pathogen? - correct answer. Carbapenem
Avycaz
Pencillins and Cephalosporins and carbapenem MOA - correct answer. Cell wall
inhibitors
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