TEST BANK FOR
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CLAYTON’S BASIC
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PHARMACOLOGY
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FOR NURSES 19TH
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EDITION BY
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WILLIHNGANZALL
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CHAPTERS
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, TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY FOR
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NURSES 19TH Edition by Willihnganz w w w w
Chapter 1: Drug Definitions, Standards, and Information Sources Test
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Bank
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MULTIPLE CHOICE w
1. What is the name under which a drug is listed by the U.S. Food and Drug Administration
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(FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C w
The official name is the name under which a drug is listed by the FDA. The brand name, or
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trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,
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name is provided by the U.S. Adopted Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 1 OBJ: w w w
2
TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
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2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database w w w
c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts w w
ANS: C w
United States Pharmacopoeia/National Formulary contains information specific to
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nutritional supplements. USP Dictionary of USAN & International Drug Names is a
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compilation of drug names, pronunciation guide, and possible future FDA approved drugs; it
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does not include nutritional supplements. Natural Medicines Comprehensive Database
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contains evidence based information on herbal medicines and herbal combination products;
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it does not include information specific to nutritional supplements. Drug Interaction Facts
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contains comprehensive information on drug interaction facts; it does not include nutritional
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supplements.
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DIF: Cognitive Level: Knowledge REF: p. 2 w w w
OBJ: 4
TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Physiological Integrity
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3. What is the most comprehensive reference available to research a drug interaction?
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a. Drug Facts and Comparisons w w w
b. Drug Interaction Facts w w
c. Handbook on Injectable Drugs w w w
d. Martindale—The Complete Drug Reference w w w
ANS: B w
, First published in 1983, Drug Interaction Facts is the most comprehensive book available on
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drug interactions. In addition to monographs listing various aspects of drug interactions, this
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information is reviewed and updated by an internationally renowned group of physicians
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and pharmacists with clinical and scientific expertise.
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DIF: Cognitive Level: Comprehension REF: p. 3 w w w
OBJ: 3
TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Physiological Integrity
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4. The physician has written an order for a drug with which the nurse is unfamiliar. Which
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section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this
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drug?
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a. Manufacturer’s section w
b. Brand and Generic Name section w w w w
c. Product Category section w w
d. Product Information section w w
ANS: B w
A physician’s order would include the brand and/or generic name of the drug. The
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alphabetic index in the PDR would make this section the most user friendly. Based on a
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physician’s order, manufacturer’s information and classification information would not be
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known. The Manufacturer’s section is a roster of manufacturers. The Product Category
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section lists products subdivided by therapeutic classes, such as analgesics, laxatives,
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oxytocics, and antibiotics. The Product Information section contains reprints of the package
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inserts for the major products of manufacturers.
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DIF: Cognitive Level: Comprehension REF: p. 3 w w w
OBJ: 4
TOP: Nursing Process Step: Planning
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MSC: NCLEX Client Needs Category: Physiological Integrity
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5. Which online drug reference makes available to health care providers and the public a
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standard, comprehensive, up to date look up and downloadable resource about medicines?
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a. American Drug Index w w
b. American Hospital Formulary w w
c. DailyMed
d. Physicians’ Desk Reference (PDR) w w w
ANS: C w
DailyMed makes available to health care providers and the public a standard,
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comprehensive, up to date look up and downloadable resource about medicines. The
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American Drug Index is not appropriate for patient use. The American Hospital Formulary is
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not appropriate for patient use. The PDR is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 4 w w w
OBJ: 5
TOP: Nursing Process Step: Implementation
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MSC: NCLEX Client Needs Category: Physiological Integrity
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) w w w w w w
b. Durham Humphrey Amendment (1952) w w w
c. Controlled Substances Act (1970) w w w
, Downloaded by: samueloronaso | samuelorona.so@gmail.com w w w w
d. Kefauver Harris Drug Amendment (1962) w w w w
ANS: A w
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
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safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
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and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
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cannot be used safely without medical supervision and restricts their sale to prescription by
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a licensed practitioner. The Controlled Substances Act addresses only controlled substances
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and their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and
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greater drug safety. Drug manufacturers are required to prove to the FDA the effectiveness
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of their products before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 4 w w w
OBJ: 8
TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Physiological Integrity
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7. Meperidine (Demerol) is a narcotic with a high potential for physical and w w w w w w w w w w w
psychological dependency. Under which classification does this drug fall?
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a. I
b. II
c. III
d. IV
ANS: B w
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
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severe psychological and physical dependence. Schedule I drugs have high potential for
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abuse and no recognized medical use. Schedule III drugs have some potential for abuse. Use
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may lead to low to moderate physical dependence or high psychological dependence.
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Schedule IV drugs have low potential for abuse. Use may lead to limited physical or
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psychological dependence.
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DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: w w w w w w w
7
TOP: Nursing Process Step: Assessment
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MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
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What would the FDA do to expedite drug development and approval for an
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outbreak of smallpox, for which there is no known treatment? a. List w w w w w w w w w w w
smallpox as a health orphan disease. w w w w w w
b. Omit the preclinical research phase. w w w w
c. Extend the clinical research phase. w w w w
d. Fast track the investigational drug. w w w w
ANS: D w
Once the Investigational New Drug Application has been approved, the drug can receive
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highest priority within the agency, which is called fast tracking. A smallpox outbreak would
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become a priority concern in the world. Orphan diseases are not researched in a priority
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manner. Preclinical research is not omitted. Extending any phase of the research would
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mean a longer time to develop a vaccine. The FDA must ensure that all phases of the
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preclinical and clinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge w w
REF: p. 7 w
OBJ: 8
TOP: Nursing Process Step: Assessment
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