NURS 1140: Exam 1 Questions and Answers Already Passed
0 view 0 purchase
Course
NURS 1140:
Institution
NURS 1140:
NURS 1140: Exam 1 Questions and
Answers Already Passed
What is pharmacokinetics?
Pharmacokinetics refers to how the body absorbs, distributes, metabolizes, and excretes a
drug.
What is the first-pass effect?
The first-pass effect is the process where a drug is metabolized at a specific ...
NURS 1140: Exam 1 Questions and
Answers Already Passed
What is pharmacokinetics?
✔✔Pharmacokinetics refers to how the body absorbs, distributes, metabolizes, and excretes a
drug.
What is the first-pass effect?
✔✔The first-pass effect is the process where a drug is metabolized at a specific location in the
body, reducing its concentration before it reaches systemic circulation.
Why is half-life important in pharmacology?
✔✔Half-life determines how long it takes for the concentration of a drug to reduce by half in the
bloodstream, influencing dosage intervals.
What is the difference between an agonist and an antagonist?
✔✔An agonist binds to a receptor and activates it to produce a biological response, while an
antagonist blocks or dampens the receptor's action.
1
,What factors can influence drug absorption?
✔✔Factors include the route of administration, blood flow to the absorption site, and the drug’s
solubility and formulation.
How does protein binding affect drug action?
✔✔Drugs bound to plasma proteins are inactive and cannot exert therapeutic effects until they
are released into free form in the bloodstream.
What is the significance of therapeutic index in pharmacology?
✔✔The therapeutic index measures the safety margin of a drug, comparing its effective dose to
its toxic dose. A wider index indicates a safer drug.
How do liver enzymes affect drug metabolism?
✔✔Liver enzymes, primarily cytochrome P450, metabolize drugs, transforming them into more
water-soluble compounds for excretion.
What is bioavailability?
✔✔Bioavailability is the proportion of a drug that enters circulation and can have an active
effect after administration.
2
, Why are loading doses sometimes required?
✔✔Loading doses are given to quickly achieve a therapeutic drug concentration in the body,
especially when immediate drug action is needed.
What is the role of the kidneys in drug excretion?
✔✔The kidneys filter and excrete drugs and their metabolites from the body, primarily through
urine.
How does age affect drug metabolism and excretion?
✔✔Older adults often have reduced liver and kidney function, slowing drug metabolism and
excretion, leading to longer drug effects and possible toxicity.
What is polypharmacy, and why is it a concern?
✔✔Polypharmacy is the use of multiple medications by a patient, which can increase the risk of
drug interactions and adverse effects.
What is the difference between a side effect and an adverse effect?
3
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller BrilliantScores. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
