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NURP 424 Pharm Exam 1 Study Guide with Complete Solutions $12.49   Add to cart

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NURP 424 Pharm Exam 1 Study Guide with Complete Solutions

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NURP 424 Pharm Exam 1 Study Guide with Complete Solutions Considerations when prescribing: - Answer-I: Indication C: contraindication P: precautions or interactions C: cost/compliance E: efficacy A: adverse effects D: dose/duration/directions Drug approval process: Phase I - Answer-Phase I...

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  • October 6, 2024
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NURP 424 Pharm Exam 1 Study Guide
with Complete Solutions

Considerations when prescribing: - Answer✔✔-I: Indication


C: contraindication


P: precautions or interactions


C: cost/compliance


E: efficacy


A: adverse effects


D: dose/duration/directions


Drug approval process: Phase I - Answer✔✔-Phase I: safety and safe dosage- how the drug is tolerated at

different doses- does not determine efficacy; studies the pharmacokinetics of the drug


(After the preclinical animal testing phase)


Drug Approval Process: Phase II - Answer✔✔-Phase II: determine dosage and efficacy; determine short-

term risks


Drug Approval Process: Phase III - Answer✔✔-Phase III: controlled and uncontrolled clinical trials of

safety and efficacy in multiple settings; submit a new drug application (NDA) to the FDA


-Is it better than current treatment?



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Drug Approval Process: Post Market - Answer✔✔-Phase IV or Post market research: has no fixed

duration, further report adverse events


DEA Controlled Drug Schedules: Schedule 1 - Answer✔✔-- No accepted medical use


-No legal use permitted


- For registered research facilities only


Heroin, LSD, mescaline, peyote, marijuana*(state to state)


DEA Controlled Drug Schedules: Schedule 2 - Answer✔✔--No refills permitted (only 30 day supply)


-No phone orders unless you have a written one within 7 days


-E-prescribe is OK


- expires in 72hrs id not filled


Narcotics, stimulants, depressants (phenobarbital, secobarbital)


DEA Controlled Drug Schedules: Schedule 3 - Answer✔✔--must be rewritten after 6 months or five refills


-phone and fax OK


Some narcotics (Percocet, hydrocodone) Some stimulants (benzphetamine, chlorpheniramine,

diethylpropion)


Anabolic steroids, testosterone


DEA Controlled Drug Schedules: Schedule 4 - Answer✔✔--same as schedule 3, penalties for illegal

possessions are different



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FIRST PUBLISH SEPTEMBER 2024


-low potential for abuse per DEA


pentazocine, phentermine, benzos, meprobamate


DEA Controlled Drug Schedules: Schedule 5 - Answer✔✔-- same as all prescription drugs


-may be dispensed without prescription unless regulated by the state


loperamide, cough meds, pregabalin


Adverse Drug Reactions: Pharmacological - Answer✔✔-- majority of adverse reactions


-predictable


-dose-related


-85-90% of ADRs


(Hypotension from antihypertensives)


Adverse Drug Reactions: Idiosyncratic - Answer✔✔--unpredictable


-Not dose-related


(Stevens-Johnson syndrome from lamictal or ibuprofen)


Immune-Mediated ADR: Type 1 - Answer✔✔--igE mediated, immediate type


-previously sensitize person


-hypersensitivity like atopic dermatitis, hives, angioedema or anaphylaxis


Immune-Mediated ADR: Type 2 - Answer✔✔-- antibody-dependent cytotoxicity


- "autoimmune response"

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