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NURP-424- Exam 3 Questions and Answers |100% Pass

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NURP-424- Exam 3 Questions and Answers |100% Pass Factors that Affect BP - Answer-- Cardiac output - Peripheral resistance - Heart rate - Filling pressure - Contractility - Arteriolar tone - Blood volume - Venous tone Blood Pressure Medicine Action - Answer-Reduce blood pressure by loweri...

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  • October 6, 2024
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EmillyCharlotte
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FIRST PUBLISH SEPTEMBER 2024




NURP-424- Exam 3 Questions and
Answers |100% Pass

Factors that Affect BP - Answer✔✔-- Cardiac output


- Peripheral resistance


- Heart rate


- Filling pressure


- Contractility


- Arteriolar tone


- Blood volume


- Venous tone


Blood Pressure Medicine Action - Answer✔✔-Reduce blood pressure by lowering cardiac output and

peripheral resistance


ACE Inhibitors (-prils) - Answer✔✔-- Block conversion of angiotensin I to angiotensin II which inhibits

aldosterone and in return lowers BP by:




- Decreasing output of the sympathetic nervous system


- Increasing vasodilation of vascular smooth muscle


Page 1/40

,EMILLYCHARLOTTE 2024/2025 ACADEMIC YAER ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISH SEPTEMBER 2024


- Decreasing retention of sodium and water (by decreasing aldosterone in the system)




- Inhibit the degradation of bradykinin (anti-inflammatory mediator - the cause of the cough and

angioedema) and increase the synthesis of vasodilating prostaglandins


ACE Inhibitor Indications - Answer✔✔-- HTN: less SE in Caucasian decent




- Hypertensive proteinuric diabetes: helps with renal protection and prevention of nephropathy




- Angina and ischemic heart disease: decreases peripheral vascular resistance which decrease cardiac

output; decrease the thickening of the ventricular walls which leads to less O2 demand




- Post-MI: reduce morbidity and mortality by reducing myocardial injury and preventing ventricular

remodeling




- HF: reduce remodeling of the heart due to HTN


ACE Inhibitor Caution & Conraindications - Answer✔✔-- Avoid in bilateral renal artery stenosis




- Avoid in idiopathic and hereditary angioedema




Page 2/40

,EMILLYCHARLOTTE 2024/2025 ACADEMIC YAER ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISH SEPTEMBER 2024


- Avoid in pregnancy and lactation




- Avoid concurrent use of ACE-I with ARB or aliskern




- Caution in renal and hepatic impairment




- Limited data for < 6 y.o. for HTN treatment. Approved for > 6 y.o.


ACE Inhibitor Adverse Effects - Answer✔✔-- Dry cough


- Hypotension


- Hyperkalemia


- Skin rash


- Altered taste


- Dizziness


- HA


- Fatigue


ARBs (-sartans) - Answer✔✔-- Indications: HTN, hypertensive proteinuric diabetes, angina and ischemic

heart disease, post-MI, HF




Page 3/40

, EMILLYCHARLOTTE 2024/2025 ACADEMIC YAER ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISH SEPTEMBER 2024


- Pharmacodynamics: block angiotensin II receptors and reduce the levels of aldosterone secretion which

reduces the retention of sodium and water




- No effect on bradykinin so less likely to develop a cough or angioedema


ARBs Caution & Contraindications - Answer✔✔-- Avoid in bilateral renal artery stenosis




- Avoid in idiopathic and hereditary angioedema




- Avoid concurrent use of ACE-I with ARB or aliskern




- Caution with other medications that cause hyperkalemia




- Caution in renal and hepatic impairment




- Approved for > 6 y.o.


ARBs Adverse Drug Effects - Answer✔✔-- Dizziness


- Hypotension


- Hyperkalemia


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