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NPN 621 EXAM 2 PHARMACOKINETICS/DYNAMICS LATEST UPDATED
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NPN 621 EXAM 2 PHARMACOKINETICS/DYNAMICS LATEST UPDATED...
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NPN 621 EXAM 2 PHARMACOKINETICS/DYNAMICSLATEST UPDATED
pharmacokinetics - ANSWER what the body does to the drug
Phase I metabolism - ANSWER CYP450 system
phase II metabolism - ANSWER conjugation--increases water solubility
for excretion; glucuronidation, acetylation
AST normal range - ANSWER 0-35
ALT normal range - ANSWER Males 10-55; Females 7-30 U/L
Bilirubin normal range - ANSWER 1-12 mg/dL
albumin normal range - ANSWER 3.5-5
acidic urine promotes excretion of - ANSWER basic drugs
alkaline urine promotes excretion of - ANSWER acidic drugs
half life - ANSWER how long it takes for metabolism and excretion of a
drug to reduce blood concentration by half
steady state - ANSWER drugs will reach a consistent blood level after 4
half lives
pharmacodynamics - ANSWER what the drug does to the body
ligand gated ion channels - ANSWER change polarization of cell
membrane
g protein linked receptors - ANSWER influence multiple operations of
the cell
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