Exam (elaborations)
PCB 3233 EXAM 2 questions with complete solutions
- Course
- PCB 3233
- Institution
- University Of Central Florida
PCB 3233 EXAM 2 questions with complete solutions
[Show more]
Content preview
PCB 3233 EXAM 2Induced innate immune response - correct answer ✔✔-Inflammation
-Leukocytes called into the site of infection
-Soluble molecules made and secreted into the blood and brought to the site of the infection
Leukocytes in the order to action - correct answer ✔✔1. Neutrophils - Mass quantities
2. Monocytes
3.Lymphocytes - days later
2 cell type recognition - correct answer ✔✔1. NK - looking at your own cells
2. Macrophages - looking at pathogen directly
Macrophages - correct answer ✔✔use toll like receptors and phagocytic receptors
PAMP - correct answer ✔✔pathogen associated molecular patterns - on pathogen
PRR - correct answer ✔✔pattern recognition receptors - on leukocyte
Are there different receptor used for phagocytosis vs. cytokine creation and secretion(signalling)? -
correct answer ✔✔yes
What are the 5 cytokines? - correct answer ✔✔IL-1
TNF-a
IL-6
CXCL8
IL-12
,Which cytokines are pyrogens? - correct answer ✔✔IL-1
TNF-a
IL-6
What do heat cytokines (Pyrogens) lead to? - correct answer ✔✔Lead to fever
Which cytokines activate endothelial cells? - correct answer ✔✔IL-1 and TNF-a
What does the activation of endothelial cells lead to? - correct answer ✔✔Vasodilation and Vascular
premeability
NK cells provides an early response for which kind of infection? - correct answer ✔✔Viral Infection
NK recognizes two types of receptors - correct answer ✔✔Activating receptors and inhibitory receptors
Activating receptors recognize - correct answer ✔✔(Stress induced) activating ligands which leads to
apoptosis.
Inhibitory receptors recognizes - correct answer ✔✔MHC 1 on all nucleated cells.
1st effector cell - correct answer ✔✔Resident Macrophages which is prevalent in connective tissues
CR1 (complement receptor 1) binds to? - correct answer ✔✔C3b
C3b is degraded by what to become iC3b? - correct answer ✔✔Factor I
NK cells can detect? - correct answer ✔✔MHC molecules
Which receptor can recognize both Gram(-) and Gram(+)? - correct answer ✔✔Scavenger Receptor A
(SR-A)
, Which leukocyte would be first out to the sight of infection in mass quantities? - correct answer
✔✔Neutrophils
Macrophages Receptors (PRR): - correct answer ✔✔Mannose Receptor
CR-3
CR-4
Dectin-1
SR-A (Scavenger Receptor-A)
SR-B (Scavenger Receptor - B)
LPS (also known as CD14)
TLR
MARCO
Can all nucleated cells use MHC 1? - correct answer ✔✔yes
Macrophages are longlived compared to what? - correct answer ✔✔Neutrophils
What can CR1 do for you? - correct answer ✔✔Bind to C3b and phagocytose what ever C3b is bound to
What are the 4 TLRs(Toll-Like Receptors)? - correct answer ✔✔TLR-3
TLR-7
TLR-5
TLR-4
What are the internal TLRs? - correct answer ✔✔TLR-3:Double stranded Viral RNA
TLR-7: Single stranded Viral RNA
What does CR-3 and CR-4 recognize? - correct answer ✔✔iC3b and LPS
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Sakayobako30. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $17.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
62890 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now