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NURS5315-Advance Pathophysiology Test 2024 | Questions Solved 100% Correct-Verified Answers
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NURS5315-Advance Pathophysiology Test 2024 | Questions Solved 100% Correct-Verified Answers
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NURS5315-Advance Pathophysiology Test2024 | Questions Solved 100% Correct-Verified
Answers
Cell injury: hypoxic ischemic injury - ✔✔Mitochondrial injury. Decreased ATP production.
ATP fails. Pump fails. ER fails.
Calcium influx injury - ✔✔Increase Ca and Na= intracellular edema. Damage to cell
membrane. Intracellular enzyme activation= cell death.
Cell injury manifestations - ✔✔lysosomes digest cytoplastic reticulum. Cell contents leak out.
Acidic = lactic acidosis. high troponins. transaminases.
Reperfusion injury - ✔✔creates reactive oxygen species (ROS). Vit C, E, flavonoids, & beta
carotene my
oxadative stress - ✔✔Chronic inflammation.
Cell injury: chemical agents - ✔✔Tylenol. vanc (renal). cephalosporin (safe). Quinolones
(tendon rupture and nerve damage)
Tumor - ✔✔Abnormal mass of tissue
Benign - ✔✔Non cancerous. Do not spread. Clear boundaries.
Malignant - ✔✔Cancerous growths. Invade nearby tissues. Spread. Rapid growth. Unclear
boundaries.
, Neoplasm - ✔✔New and abnormal growth of tissue. Benign or malignant.
Benign tumor examples - ✔✔lipoma, fibroids, adenomas
Malignant tumor examples - ✔✔Carcinomas, sarcomas, leukemia
Cancer - ✔✔Any malignant growth or tumor caused by abnormal and uncontrolled cell
division
Anaplastic - ✔✔Poorly differentiated. Do not resemble normal cells. More malignant.
Contact inhibition - ✔✔Healthy cells stop dividing when they contact other cells
Grow in a suspension - ✔✔Cancer cells do not need a sold surface to proliferate.
Long life span - ✔✔Cancer cells evade apoptosis.
Cancer cell metabolism - ✔✔Rapid division and survive in suboptimal environment. Utilize
nutrients from their environment aggressively. May damage cell. Rely on glycolysis. Can
synthesize lipids and cellular components.
Pleomorphic - ✔✔Variability in size and shape.
glycolysis - ✔✔anaerobic metabolism
Cancer stem cells - ✔✔promote tumor initiation, maintenance, and resistance to therapy.
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