Exam (elaborations)
Immuno Exam 4 (Wiegel) PCB 3233 correctly answered already passed
- Course
- PCB 3233
- Institution
- University Of Central Florida
Immuno Exam 4 (Wiegel) PCB 3233 correctly answered already passed
[Show more]
Content preview
Immuno Exam 4 (Wiegel) PCB 3233bone marrow; thymus - correct answer ✔✔T-cells originate from the _______________ and maturate in
the _______________.
VJ - correct answer ✔✔What gene segments are rearranged for the alpha chain?
VDJ - correct answer ✔✔What gene segments are rearranged for the beta chain?
yes - correct answer ✔✔Are the RAG genes used in rearrangement?
TCR-beta & pre-T alpha - correct answer ✔✔What makes up a pre-TCR?
IL7 - correct answer ✔✔A cytokine secreted by the thymic stromal cells; binds on CD34 progenitor cells;
during thymocytic commitment.
Notch-1 - correct answer ✔✔Thymocytic cell surface receptor; interacts with transmembrane ligands on
thymic epithelial cells.; lead T-cells to differentiation.
DiGeorge - correct answer ✔✔The ______________________ syndrome is caused by a failure of
development of the thymus.
22 - correct answer ✔✔The failure to develop the thymus is due to a deletion on chromosome
_________.
negative - correct answer ✔✔Double-_______________ thymocytes are called so because they DONT
have both CD4 & CD8.
recombination - correct answer ✔✔RAG 1 & 2 are also working on somatic _______________________
of the T-cell genes.
, 12/23 - correct answer ✔✔The _______________ rule states that
first - correct answer ✔✔Positive selection occurs _____________, followed by negative selection.
both - correct answer ✔✔Positive and negative selection _______________ occur in the thymus.
outlive - correct answer ✔✔T-cells_______________ B-cells.
12; 1; 2 - correct answer ✔✔If you are heterozygous for the HLA genes, you have a total of _________
molecules; 6 from class ______ and 6 from class ______.
120000 - correct answer ✔✔Heterozygotic HLA genes can lead to around _______________ peptides.
before - correct answer ✔✔γ:δ T-Cell: functional γ:δ receptor is made ____________ β chain
Pre T Cell - correct answer ✔✔____________________ Receptor: β chain is made before γ:δ receptor
negative thymocytes - correct answer ✔✔α:β T-Cell: makes α:β receptor before γ:δ receptor;
_________________________ first and then positive.
deletion - correct answer ✔✔_______________ of δ-chain genes happens after α-chain genes are
rearranged.
not - correct answer ✔✔Deletion of δ-chain genesis ________ relative to whether or not rearrangement
was productive.
one - correct answer ✔✔α:β Lineage: ______ productive gene arrangement
two - correct answer ✔✔γ:δ Lineage: _______ productive gene arrangements
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Sakayobako30. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $14.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
76747 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now