adrenergic️️Adjectival form of adrenaline, also called epinephrine (EPI). May be used broadly
to include both NE- and EPI-related features.
albuterol (Ventolin)️️Drug that selectively stimulates the β-adrenoceptor. It is used in asthma
treatments.
α-methyl-para-tyrosine (AMPT)️️Dr...
Psychopharmacology: Drugs, the Brain, and Behavior: Chapter 5
with comprehensive Questions and Answers
adrenergic✔️✔️Adjectival form of adrenaline, also called epinephrine (EPI). May be used broadly
to include both NE- and EPI-related features.
albuterol (Ventolin)✔️✔️Drug that selectively stimulates the β-adrenoceptor. It is used in asthma
treatments.
α-methyl-para-tyrosine (AMPT)✔️✔️Drug that inhibits TH activity, thereby reducing
catecholamine synthesis.
amphetamine✔️✔️Psychostimulant that acts by increasing catecholamine release in nerve cells.
apomorphine✔️✔️Drug that is a D1 and D2 receptor agonist and causes behavioral activation. It
may also be used to treat erectile dysfunction by acting through DA receptors in the brain to
increase penile blood flow.
aromatic amino acid decarboxylase (AADC)✔️✔️Enzyme that catalyzes the removal of a carboxyl
group from certain amino acids. It is responsible for the conversion of DOPA to DA in
catecholaminergic neurons and the conversion of 5-HTP to 5-HT in serotonergic neurons.
atomoxetine (Strattera)✔️✔️Selective norepinephrine uptake inhibitor used in the treatment of
ADHD.
behavioral supersensitivity✔️✔️An increased response to a drug treatment as a direct result of
previous drug history or drug intake.
biogenic amine✔️✔️A transmitter that is made by a living organism and contains at least one
amine group.
, catalepsy✔️✔️State characterized by a lack of spontaneous movement. It is usually associated
with D2 receptor blockers (a DA receptor subtype), but can also be induced with a D1 blocker.
catechol-O-methyltransferase (COMT)✔️✔️One of the enzymes responsible for metabolic
breakdown of catecholamines.
catecholamines✔️✔️Group of neurotransmitters and hormones characterized by two chemical
similarities: a core structure of catechol and a nitrogen-containing amine. They belong to a wider
group of transmitters called monoamines or biogenic amines.
clonidine (Catapres)✔️✔️An α2-adrenergic agonist that stimulates autoreceptors and inhibits
noradrenergic cell firing. It is used to reduce symptoms of opioid withdrawal.
cocaine✔️✔️Stimulant drug that blocks reuptake of DA, NE, and 5-HT by neurons, thereby
increasing their concentration in the synaptic cleft.
DA transporter (DAT)✔️✔️Protein in the membrane of dopaminergic neurons that is responsible
for DA uptake from the synaptic cleft.
dexmedetomidine (Precedex)✔️✔️Drug that stimulates α2-receptors, characterized by its sedative,
anxiolytic, and analgesic effects. It is used to treat surgical patients in intensive care.
dopamine (DA)✔️✔️Neurotransmitter, related to NE and EPI, that belongs to a group called
catecholamines.
dopamine β-hydroxylase (DBH)✔️✔️Enzyme that catalyzes the third step of NE synthesis in
neurons, the conversion of DA to NE.
dopaminergic✔️✔️Adjectival form of DA.
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