Blood Bank - Blood Group Systems Practice Questions with
Complete Solutions/ Latest Update 2024.
What ABO phenotype will exist in an individual that inherits an A gene from one parent and a B gene
from the other?
A. A
B. B
C. AB
D. O - ANS - C
Which of the following is the most prevalent blood type found in the United States?
A. O positive
B. A positive
C. B positive
D. O negative - ANS - A
What is his MOST likely genotype for a white male who has the following Rh antigens C, c, D, E, e?
A. R1r
B. R1R2
C. Roar
D. rare" - ANS - B
Why is it dangerous to transfuse a blood group O person with a unit of blood group A?
A. The patient will make antibodies to the type A blood.
B. The group A blood may become the prominent blood group.
C. The patient's Anti-O would destroy the donor's cells with severe consequences to the patient.
, 2
D. The patient's anti-A would destroy the donor's cells with severe consequences to the patient. - ANS -
D
How are antibodies to the ABO blood group antigens unique?
A. Laboratory tests are available for their identification
B. The antibodies are naturally occurring to antigens that are absent from the red cell membrane
C. The antibodies are formed after the individual has been immunized
D. The antibodies are IgM - ANS - B
The serum of which of the following individuals may agglutinate group A1 cells?
A. A2 individual
B. A1B individual
C. A1 individual
D. Newborn - ANS - A
The serum from a patient of African-American descent is reactive with all screening and panel cells.
Which antibody directed to a high incidence antigen is most likely to be present?
A. Anti-Lob
B. Anti-Jk3
C. Anti-U
D. Anti-Ku - ANS - C
Phenotype refers to:
A. The genes inherited from each parent
B. Opposing antigens produced by genes
C. The presence of two or more alleles at a locus
D. The expression of traits - ANS - D
, 3
The McLeod phenotype is associated with which of the following antigen systems?
A. Rh
B. P
C. Kell
D. MNSs - ANS - C
In immunohematology, an antithetical relationship exists between M antigen and which of these
antigens?
A. K antigen
B. S antigen
C. Lu6 antigen
D. N antigen - ANS - D
Which specific immunodominant sugar is responsible for A (blood group A) antigenic specificity?
A. L-fucose
B. D-galactose
C. N-acetyl-D-galactosamine
D. Glucose - ANS - C
In which group is Type B blood found in higher frequency?
A. African Americans
B. Caucasians
C. Asians
D. Hispanics - ANS - C
Which genotype(s) is/are possible for a mating of an AB mother and an AB father?
A. AB only
B. AA and BB
C. AB, AA, and BB
, 4
D. All genotypes are possible - ANS - C
Which one of these Lewis blood group system phenotypes usually produces anti-Lea?
A. Le(abs+)
B. Le(abs-)
C. Le(a-b+)
D. Le(a-b-) - ANS - D
Lewis Blood Group System is a human blood group unlike most others. The antigen is produced and
secreted by exocrine glands, eventually adsorbing to the surface of red blood cells. Its expression is
based on the genetic expression of the Lewis and Secretor genes.
Based on the following genotype (Le) (sese), what would you predict the Lewis antigen phenotypic
expression to be?
A. Le (a- b-)
B. Le (a+ b+)
C. Le (a+ b-)
D. Le (a- b+) - ANS - C
A specimen from a 23-year-old female patient who is a Bombay phenotype arrives in the blood bank.
You observe the following reactions upon tube testing.
Anti-A - 0
Anti-B - 0
A cell - 4+
B cells - 4+
Which of the following statements is true?
A. Type AB red blood cells can be transfused to this patient
B. Type O red blood cells can be transfused to this patient in an emergency
C. Type O NEG blood can be transfused to this patient
D. Patient can receive only Bombay phenotype blood - ANS - D
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