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BIO 2170 FINAL EXAM REVIEW QUESTIONS AND COMPLETE SOLUTIONS.
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Methylases - Answer adds methyl group to restriction sites on cell's own DNA (blocks cleavage) Silent mutation - Answer No change in amino acid sequence Nonsense mutation - Answer Introduction of stop codon Missense mutation - Answer Amino acid change at position Dispersive ...

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  • October 10, 2024
  • 15
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • Bio 2170
  • Bio 2170

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BIO 2170 FINAL EXAM REVIEW
QUESTIONS AND COMPLETE
SOLUTIONS.
Methylases - Answer adds methyl group to restriction sites on cell's own DNA (blocks cleavage)



Silent mutation - Answer No change in amino acid sequence



Nonsense mutation - Answer Introduction of stop codon



Missense mutation - Answer Amino acid change at position



Dispersive replication - Answer fragments of original DNA molecules are used as templates



Reciprocal translocation - Answer exchange of one part of a chromosome for another (problems in
meiosis)



Restriction enzymes - Answer usually palindromic /-sticky I-blunt



Southern blot - Answer used to detect specific sequences in DNA samples



Tumor Suppressor - Answer proteins whose normal activities inhibit cell to divide



Telomerase - Answer adds short stretch of DNA to end of chromosome to prevent shortening



checkpoints - Answer control mechanisms that ensure fidelity of cell division



PCR requires - Answer DNA template

, DNA polymerase

4 nucleoside triphosphate

2 primers



PCR is a cycle of - Answer denaturation, annealing, and extension



Aneuploidy - Answer chromosome lacking or present in excess



Polyploid - Answer organisms with complete extra sets of chromosome



Highly repetitive - Answer short repeating sequences

no coding function

(satellite)



Chromosomal mutation - Answer change in segments of DNA

loss, duplication, and rearrangement



Loss of function mutation - Answer almost always recessive

affect protein function



G1/S - Answer prepares cell for DNA replication



S cylcin - Answer initiate DNA synthesis



M cyclin - Answer prepares cell for mitosis



Restriction fragment length polymorphism - Answer result from small changes in DNA sequence
between chromosome that create to destroy restriction sites

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