B 6. BAzithromycin Bdosing Brequires Bthat Bthe Bfirst Bday’s Bdosage Bbe Btwice Bthose Bof Bthe Bother
B4 Bdays Bof Bthe Bprescription. BThis Bis Bconsidered Ba Bloading Bdose. BA Bloading Bdose:
1. Rapidly Bachieves Bdrug Blevels Bin Bthe Btherapeutic Brange
2. Requires Bfour- Bto Bfive-half-lives Bto Battain
3. Is Binfluenced Bby Brenal Bfunction
4. Is Bdirectly Brelated Bto Bthe Bdrug Bcirculating Bto Bthe Btarget Btissues
B 7. BThe Bpoint Bin Btime Bon Bthe Bdrug Bconcentration Bcurve Bthat Bindicates Bthe Bfirst Bsign Bof Ba
Btherapeutic Beffect Bis Bthe:
1. Minimum Badverse Beffect Blevel
2. Peak Bof Baction
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