PNB 2265 Final Exam UPDATED Exam Questions and CORRECT Answers
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Course
PNB 2265
Institution
PNB 2265
PNB 2265 Final Exam UPDATED Exam
Questions and CORRECT Answers
What is true about the breakdown of red blood cells? - CORRECT ANSWER- >> Iron is
carried through the plasma by transferrin
>> Bilirubin is excreted in the urine
>> Bilirubin is excreted in the bile
>> Ir...
PNB 2265 Final Exam UPDATED Exam
Questions and CORRECT Answers
What is true about the breakdown of red blood cells? - CORRECT ANSWER- ✔✔>> Iron is
carried through the plasma by transferrin
>> Bilirubin is excreted in the urine
>> Bilirubin is excreted in the bile
>> Iron is carried through the plasma by transferrin
Adult hemoglobin is composed of what components? - CORRECT ANSWER- ✔✔>> four
heme groups
>> two beta subunits
>> two alpha subunits
Infant hemoglobin is composed of what components? - CORRECT ANSWER- ✔✔>> four
heme groups
>> two alpha subunits
>> two gamma subunits
What is hemoglobinuria characterized by? - CORRECT ANSWER- ✔✔Large amounts of
hemoglobin being expected in the urine
What kinds of cells are agranulocytes? - CORRECT ANSWER- ✔✔>> Lymphocytes
>> Monocytes
,The most abundant leukocytes are ________ & the least abundant are ________ - CORRECT
ANSWER- ✔✔Neutrophil & Basophil
What is true about hemolytic disease? - CORRECT ANSWER- ✔✔>> It is caused by anti-D
antibodies crossing the placenta
>> occurs in a woman with AB- blood
>> Red blood cells in the fetus are being attacked by IgG antibodies from the mother
What is true about myeloid stem cells? - CORRECT ANSWER- ✔✔>> stimulation by EPO
causes them to differentiate into proerythroblasts
>> they have ribosomes
>> they have a nucleus
Where does Erythropoietin come from? - CORRECT ANSWER- ✔✔The kidney, to increase
RBC production
In the process of hemostasis, what is Factor-X function? - CORRECT ANSWER-
✔✔Activates a sequence of enzymatic reactions that produce the coagulation phase of
hemostasis
In the process of hemostasis, what is Tissue Factor's function? - CORRECT ANSWER-
✔✔Serves as the entry point to the extrinsic pathway
In the process of hemostasis, what is the function of Thrombin? - CORRECT ANSWER-
✔✔Converts Fibrinogen to Fibrin
, In the process of hemostasis, what is the function of Collagen? - CORRECT ANSWER-
✔✔Serves as the starting point of the intrinsic pathway- activates inactive clotting factors
when blood leaks from the blood vessel
What is hemostasis? - CORRECT ANSWER- ✔✔The process of stopping blood loss
What are the phases of hemostasis? - CORRECT ANSWER- ✔✔1. Vascular spasm
2. Platelet phase
3. Coagulation
How is Thrombin formed? - CORRECT ANSWER- ✔✔Either by the extrinsic or intrinsic
pathways
How is the extrinsic pathway initiated? - CORRECT ANSWER- ✔✔Via tissue factors that
come from damaged endothelial cells and then goes to the common pathway to form
thrombin
How is the intrinsic pathway initiated? - CORRECT ANSWER- ✔✔Via collagen that
activated clotting factors when blood leaks from blood vessels and then goes to common
pathway to form thrombin
What happens in the vascular spasm phase of hemostasis? - CORRECT ANSWER-
✔✔Damaged blood vessel constricts to minimize blood flow and releases a damage signal
What happens in the platelet phase of hemostasis? - CORRECT ANSWER- ✔✔>> Platelet
become activated
>> Platelet become sticky via adhesion
>> Platelet sends out signals to attract more platelets (aggregation)
>> Platelet forms plug to stop the bleeding
>> Platelet assists in clot formation by being activated by ADP & Thromboxane
What happens in the coagulation phase of hemostasis? - CORRECT ANSWER- ✔✔Fibrin is
formed from fibrinogen via the thrombin enzyme that is sent from the platelets
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