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BMS 108 PLQ 1 EXAM STUDY GUIDE
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BMS 108 PLQ 1 EXAM STUDYGUIDE
Synapse - Answer The junction between a neuron and a target cell
1. Muscle cell — neuromuscular junction
2. Gland cell— neuroglandular junction
3. Neuron— neuronal junction - Answer Three types of target cells that have synapses
1. Pre-synaptic neuron with pre-synaptic membrane (axon terminal)
2. Synaptic cleft (space between the neuron and a target cell)
3. Post-synaptic cell with post-synaptic membrane (e.g. dendrite in a neuronalsynapse) -
Answer The components of all synapses are:
Neurotransmitters - Answer When an action potential arrives at the terminal bouton, a
sequence of events occurs that leads to the release of specialized chemicals, called
_______________________________, that changes the electrical impulse into a chemical
one. The neurotransmitters diffuse across the synaptic cleft and result in a response in
the target cell.
action potenial; voltage gated Ca++ channels; synaptotagmin; v-snares; t-snares;
exocytosis; ligand-gated; G-protein-gated - Answer 1. An ______________________
reaches axon terminal (terminal bouton).
2. This triggers ______________________ to open by depolarizing the terminal
bouton(pre-synaptic membrane).
3. Ca++ move down their electrochemical gradient and binds to a protein called
______________________.
4. A group of proteins called _______________ (vesicular soluble N-ethylmaleimide
sensitive protein attachment protein receptor) embedded in the vesicular membrane
bind with __________________ in the pre-synaptic membrane bind with synaptotagmin.
5. The fusion of the vesicular membrane with the pre-synaptic membrane results in the
release of NTs into the synaptic cleft by ____________________.
6. NTs diffuse across and bind to specific protein receptors in the post-synaptic
membrane of the target cell.
7. The binding of NTs results in the opening of ion channels. These channels may be
________________________ or _______________________, but not voltage-gated. As long as
the ligands (NTs) remainbound, the channels remain open.
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