WGU D027 pathopharm Questions and Answers (100% Pass)
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Course
WGU D027
Institution
WGU D027
Mechanism of Action for loop diuretics
block water reasborption in the loop of Henle of nephron. Increases
urine output
Suffix for loop
-emide
ex: furosemide
cautions in using loop diuretics
decreased potassium, decreased BP, ototoxicity, nephrotoxicity
USE WITH CAUTION in those who hav...
✓ angiotensin II causes vasonconstriction and secretion of aldosterone,
which results in reabsorption of sodium/water in the nephrons
angiotensin 2 converting enzyme inhibitor (ACE inhibitor) suffix and MOA
✓ suffix: -pril example: lisinopril
MOA: inhibits ACE from converting angiotensin 1 to angiotensin 2, therefor
prevents water reabsorption
decreases cardiac workload
decreases BP
Adverse drug reactions for ACE inhibitors
✓ high potassium, angioedema, dry cough
Angiotensin Receptor Blocker (ARBs) suffix and MOA
✓ suffix: sartan example: losartan
MOA: prevent Angiotensin2 from binding to receptor sites, which then
prevents reabsorption of water and vasoconstriction
leads to lower BP
Adverse drug reactions of ARBS
Master01 | October, 2024/2025 | Latest update
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