BMS 127 Exam Questions And
Correct Answers
HSV-1 Signs and Symptoms - Answer oral and perioral vesicles that lead to ulcers,
malaise and fever
what is infected in HSV-1 - Answer multinucleated keratinocytes
when do most primary infections for HSV-1 occur - Answer childhood
where does HSV-1 take up residence - Answer trigeminal ganglion
treatment for HSV-1 - Answer acyclovir or analog
how to confirm if HSV-1 - Answer cytology, serum titers (IgM anti-HSV would be present)
which antibody is present in HSV-1 - Answer IgM
signs and symptoms of HSV-2 - Answer tingling and burning sensation, perioral skin,
lips, gingiva, palate
systemic signs in HSV-2 - Answer none
systemic signs in HSV-1 - Answer fever and malaise
what is affected by HSV-2 - Answer keratinized mucosa
where does HSV-2 remain latent - Answer trigeminal ganglion
what activates HSV-2 - Answer sunlight, menopause, stress, change in immune system
treatment for HSV-2 - Answer acyclovir
how to test for HSV-2 - Answer cytology, biopsy, serum titers for antibodies (IgG)
what would be present in HSV-2 serum titers - Answer IgG
systemic signs of varicella zoster - Answer fever, malaise
another name for varicella zoster - Answer chicken pox
signs and symptoms of varicella zoster primary - Answer vesicular eruption in trunk,
head, neck
how do you treat varicella zoster - Answer treat symptoms
signs and symptoms of varicella zoster secondary - Answer rash, vesicles, ulcers
unilaterally line along dermatome
,how to treat varicella zoster secondary - Answer acyclovir
signs and symptoms of pemphigus vulgaris - Answer intraepithelial blisters, vesicles or
bullae then ulcers that are persistent and aggressive
acantholysis - Answer damage to the glue that holds the keratinocytes together
autoimmune reaction attacks what in pemphigus vulgaris - Answer desmoglein 3
area affected in pemphigus vulgaris - Answer skin and or mucosa (first to show, last to
go) in regards to mouth
how do blisters appear in pemphigus vulgaris - Answer not intact
treatment of pemphigus vulgaris - Answer immunosuppressives
how to confirm pemphigus vulgaris - Answer direct immunofluoresence -> green fishnet
appearance
signs and symptoms of mucus membrane pemphigoid - Answer subepithelial
separation, irregular, superficial, and painful ulcers
autoimmune reaction affects what in mucus membrane pemphigoid - Answer
hemidesmosomes -> laminin 5 and BP180
area affected in mucus membrane pemphigoid - Answer oral mucosa and conjunctiva of
eye
how do blisters appear in mucus membrane pemphigoid - Answer irregular, superficial,
INTACT
treatment of mucus membrane pemphigoid - Answer control not cure with
corticosteroids, refer to eye doctor for potential scarring
how to confirm mucus membrane pemphigoid - Answer direct immunofluoresence ->
snake like line that is green
signs and symptoms of measles - Answer high fever, runny noise, cough, red eyes, tiny
red spots on body that start at head and move down body, white spots in mouth (koplik
spots)
koplik spots - Answer white spots in mouth
another name for coxsacchie A - Answer hand, foot, mouth
signs and symptoms of herpangina - Answer blisters in mouth, not hand and foot
involvement like coxsacchie A
treatment for herpangina - Answer none -> get better on own
vesicle - Answer small
,bullous - Answer big
herpetic whitlow - Answer HSV of the fingers
herpes keratitis - Answer herpes infection of the eye, can cause scarring of the cornea
and blindness
when do we start to see tombstone like appearance on histo - Answer pemphigus
vulgaris
acute traumatic ulceration appearance - Answer yellow base, red halo, history of
trauma, pain
is there pain in acute traumatic ulceration - Answer yes
is there pain in chronic traumatic ulceration - Answer normally no
appears of chronic traumatic ulceration - Answer yellow base, elevated margins
where does traumatic ulceration occur - Answer in the mouth
how to heal traumatic ulcerations - Answer baking soda and water to inc pH
histopath of traumatic ulceration - Answer inflamed granulation tissue and fibrin
what causes syphilis - Answer Treponema pallidum
primary syphilis - Answer chancre -> chronic ulcer at site of infection
secondary syphilis - Answer oral mucosa patches, condyloma latum, maculopapulary
rash
tertiary syphilis - Answer gummas (destructive ulcers), CNS and cardiovascular lesions
-> becomes autoimmune
at what stage does syphilis have an autoimmune component - Answer tertiary
syphilis congenital form - Answer abnormal shape of molars/incisors, deafness, ocular
keratitis, skeletal defects
where is primary syphilis found - Answer genital area
where is secondary syphilis found - Answer lips and mouth
where is congenital syphilis seen - Answer in and around nose, molars, incisors
what stages of syphilis have resolution with medication - Answer primary and secondary
what medication is often prescribed for syphilis - Answer penicillin and tetracyclines
gummas are a type of - Answer vasculitis
, how to confirm syphilis - Answer RPR test to see antigens in blood
signs and symptoms of TB - Answer chronic ulcers, nonhealing and indurated, often
multiple
what type of infection is TB - Answer bacterial
where is TB found - Answer apex of lungs where there is a lot of oxygen, oral lesions
usually follow
risk factors for TB - Answer overcrowding, debilitation, immunocompromised
treatment for TB - Answer combo of isoniazid, rifampin, ethambutol
histopath for TB - Answer caseating granulomas with langhans giant cells, use fite stain
staining technique for TB - Answer fite stain
what are we looking for in TB histopath - Answer mycobacteria
common example of deep fungal infection - Answer coccidioidomycosis (valley fever)
what causes valley fever - Answer inhalation of spores
signs of valley fever - Answer cough, fever, weight loss, chronic non healing ulcers
initial site of valley fever - Answer lungs because inhaled
where does valley fever travel to - Answer mouth when you cough it up
treatment for valley fever - Answer ketocanazole, fuluconazole, itracanazole,
amphotericin B
what mucosa do recurrent aphthous ulcers target - Answer non keratinized mucosa
(lining mucosa)