PC707 Final Safety Exam - Liane's Flashcards Questions And Complete Answers
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Course
PC707
Institution
PC707
PC707 Final Safety Exam - Liane's
Flashcards Questions And Complete Answers
Describe safe and ethical prescribing for family and friends *if* you do it, treat as any
patient
full history, exam, etc
Rx only with *extreme* caution if even allowed in your state
Understand pregnancy letter cate...
PC707 Final Safety Exam - Liane's
Flashcards Questions And Complete Answers
Describe safe and ethical prescribing for family and friends *if* you do it, treat as any
patient
full history, exam, etc
Rx only with *extreme* caution if even allowed in your state
Understand pregnancy letter categories and PLLR Categories A, B, C, D, X
--phasing out, too confusing
PLLR is more comprehensive and specific about known risks
Immune-mediated adverse drug reactions (hypersensitivity rxn) Type 1: immediate, IgE,
anaphylaxis
Type 4: delayed, t-cell, dermatitis, SJS
Understand agonist/antagonist and receptor site activity Agonist=activates receptor
Antagonist=blocks drug from binding to receptor
, PC707 Final Safety Exam - Liane's
Flashcards Questions And Complete Answers
Know term - absolute contraindication Risk always outweighs benefit, never give
Know term - relative contraindication Benefit *may* outweigh risk
Know term - precaution =warnings
Understand med reconciliation and safety Review meds at *every* visit for changes
-including supplements
-medicinal foods
-polypharmacy (5+ concurrent meds)
-increased risk of adverse reaction
Understand how physiologic changes in the elderly impact prescribing Small liver mass--
Same with kidneys - less mass and capability to break down and clear drugs, remain in blood
stream longer
, PC707 Final Safety Exam - Liane's
Flashcards Questions And Complete Answers
Understand how physiologic changes in peds impact prescribing neonates/infants have
immature metabolic capacity, cannot break down and clear drugs as well as everyone else
Review OTC meds regarding safety in pregnant women and peds -Not well known r/t lack
of research
-few "A" drugs: acetaminophen, 1st gen antihistamines
-pediatric formulation important, may have same name as for adults but contain different active
ingredient
What is BEERS list and STOPP tool and use implications -guidelines of rx'ing to those
65+
-identifies Potentially Inappropriate Medications
-not hard rules, but considerations
Genomics: Poor metabolizer No alleles to metab drug
Active drug: increased exposure b/c not metabolized out of body
, PC707 Final Safety Exam - Liane's
Flashcards Questions And Complete Answers
Prodrug: decreased exposure b/c not metabolized into active form
Genomics: Intermediate metabolizer Decreased alleles to metab drug
Active drug: increased exposure b/c not metabolized out of body as efficiently
Prodrug: decreased exposure b/c not metabolized into active form
Genomics: Extensive metabolizer Has typical alleles for drug metabolism
Normally metabolizes active drugs and prodrugs
Genomics: Ultrarapid metabolizer Extra alleles to metab drug
Active drug: decreased exposure b/c metabolized out of body quickly
Prodrug: increased exposure b/c metabolized into active form quickly
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