Final Exam: NR565/ NR 565 (Latest 2023/
2024 Update) Advanced Pharmacology
Exam Review| Questions and Verified
Answers -Chamberlain
1. A patient has a TSH of .28, a free T4 of 3, and a free T3 over 650. What
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medicationshould she be started on?
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Answer: Methimazole, PTU, radioactive iodine. These labs indicatevi vi vi vi vi vi vi
hyperthyroidism. Treatment for thyroid storm: K iodide or strong
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iodinesolution to suppress thyroid release. Methimazole to suppress
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thyroid synthesis.
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2. When is it appropriate to increase insulin needs?
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Answer: Pregnancy (after first trimester), stress, infection, weight
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loss,adolescent growth spurt. DECREASE for exercise and first
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trimester. vi
3. What is the TDD of a person that weighs 70kg?
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IF a person is eating a 50 carb meal, how much insulin will be needed based on the
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TDDfrom the above question?
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Answer: 42 TDD : 21 basal 21 bolus (Wt in kg x 0.6; 50% long vi vi vi vi vi vi vi vi vi vi vi vi vi vi
actingand 50% rapid acting)
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500 divided by (the TDD) 42 = 12. (carb to insulin ratio) then
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(mealcarbs) 50 divided 12= 4.1 units with short acting insulin
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,4. "As long as the short-acting insulin is drawn up first I can mix my insulin glargine
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withit."
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Answer: Of the long-acting medications, ONLY NPH the
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intermediateduration is suitable for mixing with the short action
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insulins.vi
5. A women who is taking Pioglitazone states, "I'm glad that this medication
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promotesweight loss."
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Answer: First this medication promotes increase in LDL levels,
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whichincreases cardiovascular risk. Also, she's a female so speak
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about exercise and weight bearing exercise d/t possible increased risk
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for fractures.
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6. Glucocorticoid MOA vi
Answer: Most effective in long-term control of airway inflammation
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7. Cromolyn MOA vi
Answer: Used as prophylaxis for mild to moderate asthma
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8. Monoclonal Antibodies MOA vi vi
Answer: Used for allergy-related asthma and Eosinophilic asthma.
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Omalizumab for allergy related and Ben ralizumab, mepliz, and
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reslizare for eosinophilic
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9. Leukotriene MOA vi
, Answer: Second-line therapy to reduce inflammation vi vi vi vi vi
andbronchoconstriction
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10. B2 adrenergic agonists MOA
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Answer: Can be used PRN, for EIB, COPD exacerbations, vi vi vi vi vi vi vi vi
andmaintenance therapy
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11. methylxanthines MOA vi
Answer: Maintenance therapy for chronic stable asthma (theophylline).
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P. 570. Use ONLY if B2 or anticholinergics are not appropriate.
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12. anticholinergic MOA vi
Answer: Approved for bronchospasm related to COPD vi vi vi vi vi vi
13. •What are some risk factors of fatal asthma attacks?
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Answer: Uncontrolled, hospitalized recently, triggers,vi vi vi vi
14. •Roflumilast (select all that vi vi vi
apply)1.Reduces inflammation
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2.Not intended during
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pregnancy3.Approved for
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viasthma
4. First-line drug for COPD vi vi vi
Answer: Reduces inflammation, not intended for pregnancy,
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approvedonly for COPD, Second-line drug for COPD
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, Uses for exacerbations prophylaxis in pts with severe COPD with
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aprimary chronic bronchitis component.
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15. What pt education can you provide a patient for ICS use?
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Answer: Rinse d/t oropharyngeal candidiasis and vi vi vi vi vi
dysphonia(hoarseness, difficulty speaking).
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16. What patient teaching can a provider give when prescribing a PPI?
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Answer: Hypomagnesia symptoms: muscle cramps, tremors, cramps, vi vi vi vi vi vi
and palpitations. Check Mg levels periodically especially in the
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elderly.Get enough calcium and VIT D. call if having diarrhea (Cdiff)
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17. What patient teaching can a provider give when prescribing an H2RA?
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Answer: Report lethargy, solmnolance, restlessness, confusion or vi vi vi vi vi vi
hallucinations. (CNS effects). Teach about possible reduced libido,
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impotence, gynecomastia, pneumonia. P.594 Cimetidine interacts
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withCYP system so check with pt if they are taking warfarin,
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phenytoin, theophylline, lidocaine.
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18. A patient presents with a complaint of reflux and constipation. He states that he
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drinksenough water, and admits he has gained 30lbs. He also states that he has been
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having "reflux" type symptoms. What are your next steps for education?
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Answer: Educate that weight gain can promote reflux symptoms, vi vi vi vi vi vi vi vi
askabout any otc use such as antacids which may cause constipation.
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19. zollinger-Ellison syndrome is due to a vi vi vi vi vi producing tumor. Treatment is long- vi vi vi vi
termtherapy of what medication class?
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