Ninja PRITE Most Asked Questions With
Complete Solutions!!
60 yo right-handed M, getting lost, only writes on right half of paper. Left-sided hemi-neglect. Where
is the lesion? - ANSWERRIGHT PARIETAL LOBE
66 yo with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness, nystagmus,
hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left. Dx? - ANSWERLATERAL
MEDULLARY STROKE
26 yo w/HA and R-hand clumsiness for weeks. Exam shows difficutty w/rapid alternating movements
of hand, overt intention tremor on finger-to-nose, and mildly dysmetric finger tamping. CNS intact
and no papilledema. Where will damage show on MRI? - ANSWERCEREBELLUM
78 yo pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt appeared to be
unaware that there was a problem of weakness on one side of this body. When asked to raise the
weak arm, the patient raised his normal arm. When the failure to raise the paralyzed arm was
pointed out to pt, he admitted that the arm was slightly weak. He also neglects the side of the body
when dressing and grooming. Pt did not shave one side of his face, had difficulty putting a shirt on
when it was turned inside out. Area of the brain likely affected by stroke? - ANSWERRIGHT PARIETAL
LOBE
Adult neurogenesis happens in which area of the brain? - ANSWERHIPPOCAMPUS
Previously pleasant mom becomes profane and irresponsible over 6 months. Most likely a pathology
in: - ANSWERFRONTAL LOBE
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons
reside in which area of the brain? - ANSWERVENTRAL TEGMENTAL AREA
Orexin is made in what part of the brain? - ANSWERLATERAL HYPOTHALAMIC NUCLEI
Which dopaminergic pathway includes the nucleus accumbens and also mediates addiction and
associated behaviors/ reinforcing? - ANSWERMESOLIMBIC
, Young pt with new onset severe HAs associated with periods of visual obscuration. Neuro exam is
normal except for papilledema. MRI: normal and shows no mass effect. Next test? -
ANSWERLUMBAR PUNCTURE TO MEASURE PRESSURE
Neural plasticity is largely mediated through the capacity to rapidly change in number and
morphology of what cell structure? - ANSWERDENDRITIC SPINES
Which cell type secretes innate pro-inflammatory cytokines TNF - alpha and Il -1 B in pts with
inflammatory conditions that affect the brain? - ANSWERMICROGLIA
Cortical synaptic remodeling characteristic of normal adolescence is also believed to be associated
with what neurobiological change? - ANSWERPREFERENTIAL LOSS OF EXCITATORY SYNAPSES
DA release in what structure represents common final event associated w/ reinforcing effects of
opiates, cocaine, amphetamines, nicotine, PCP, and alcohol? - ANSWERNUCLEUS ACCUMBENS
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons
reside in which area of the brain? - ANSWERVENTRAL TEGMENTAL AREA
Neurohormone for social bonding: - ANSWEROXYTOCIN
Decreased level of what NT is most associated with depressed mood, poor sleep, and poor impulse
control, and affective aggression? - ANSWERSEROTONIN
Visual problem in pituitary tumor compressing optic chiasm: - ANSWERBITEMPORAL HEMIANOPSIA
Unsteady gait, appendicular ataxia in LE only and normal eye movement. Walks with lurching broad-
based gait. Dx? - ANSWERCEREBELLAR DEGENERATION (ALCOHOLIC)
66 yo c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On exam, mild
impairment of vertical gaze on smooth pursuit/saccades, mild axial rigidity & minimal rigidity of
upper extremities, along w/ mild slowness of movement on finger tapping, hand opening & wrist
opposition. Posture nml. Gait tentative/awkward, but w/o shuffling, ataxia, tremor. Pt is slow in
arising from a chair. Most likely dx: - ANSWERPROGRESSIVE SUPRANUCLEAR PALSY
Complete Solutions!!
60 yo right-handed M, getting lost, only writes on right half of paper. Left-sided hemi-neglect. Where
is the lesion? - ANSWERRIGHT PARIETAL LOBE
66 yo with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness, nystagmus,
hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left. Dx? - ANSWERLATERAL
MEDULLARY STROKE
26 yo w/HA and R-hand clumsiness for weeks. Exam shows difficutty w/rapid alternating movements
of hand, overt intention tremor on finger-to-nose, and mildly dysmetric finger tamping. CNS intact
and no papilledema. Where will damage show on MRI? - ANSWERCEREBELLUM
78 yo pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt appeared to be
unaware that there was a problem of weakness on one side of this body. When asked to raise the
weak arm, the patient raised his normal arm. When the failure to raise the paralyzed arm was
pointed out to pt, he admitted that the arm was slightly weak. He also neglects the side of the body
when dressing and grooming. Pt did not shave one side of his face, had difficulty putting a shirt on
when it was turned inside out. Area of the brain likely affected by stroke? - ANSWERRIGHT PARIETAL
LOBE
Adult neurogenesis happens in which area of the brain? - ANSWERHIPPOCAMPUS
Previously pleasant mom becomes profane and irresponsible over 6 months. Most likely a pathology
in: - ANSWERFRONTAL LOBE
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons
reside in which area of the brain? - ANSWERVENTRAL TEGMENTAL AREA
Orexin is made in what part of the brain? - ANSWERLATERAL HYPOTHALAMIC NUCLEI
Which dopaminergic pathway includes the nucleus accumbens and also mediates addiction and
associated behaviors/ reinforcing? - ANSWERMESOLIMBIC
, Young pt with new onset severe HAs associated with periods of visual obscuration. Neuro exam is
normal except for papilledema. MRI: normal and shows no mass effect. Next test? -
ANSWERLUMBAR PUNCTURE TO MEASURE PRESSURE
Neural plasticity is largely mediated through the capacity to rapidly change in number and
morphology of what cell structure? - ANSWERDENDRITIC SPINES
Which cell type secretes innate pro-inflammatory cytokines TNF - alpha and Il -1 B in pts with
inflammatory conditions that affect the brain? - ANSWERMICROGLIA
Cortical synaptic remodeling characteristic of normal adolescence is also believed to be associated
with what neurobiological change? - ANSWERPREFERENTIAL LOSS OF EXCITATORY SYNAPSES
DA release in what structure represents common final event associated w/ reinforcing effects of
opiates, cocaine, amphetamines, nicotine, PCP, and alcohol? - ANSWERNUCLEUS ACCUMBENS
In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons
reside in which area of the brain? - ANSWERVENTRAL TEGMENTAL AREA
Neurohormone for social bonding: - ANSWEROXYTOCIN
Decreased level of what NT is most associated with depressed mood, poor sleep, and poor impulse
control, and affective aggression? - ANSWERSEROTONIN
Visual problem in pituitary tumor compressing optic chiasm: - ANSWERBITEMPORAL HEMIANOPSIA
Unsteady gait, appendicular ataxia in LE only and normal eye movement. Walks with lurching broad-
based gait. Dx? - ANSWERCEREBELLAR DEGENERATION (ALCOHOLIC)
66 yo c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On exam, mild
impairment of vertical gaze on smooth pursuit/saccades, mild axial rigidity & minimal rigidity of
upper extremities, along w/ mild slowness of movement on finger tapping, hand opening & wrist
opposition. Posture nml. Gait tentative/awkward, but w/o shuffling, ataxia, tremor. Pt is slow in
arising from a chair. Most likely dx: - ANSWERPROGRESSIVE SUPRANUCLEAR PALSY
