a cause of false positive XM: Correct Ans-macrophage contamination
DRA can combine with _______ DRB chains Correct Ans-several different
Antigen responsible for graft loss in 1st 6 months Correct Ans-DR
antigen responsible for graft loss in first 2 years Correct Ans-HLA-B
antigen responsible for loss in long term Correct Ans-HLA-A
Functional variants are absent in what HLA loci Correct Ans-HLA-DRA
, CHT Exam with Complete Solutions
DR beta chain is encoded by _____ loci Correct Ans-4 (DRB1, DRB3, DRB4, DRB5)
Most diverse loci Correct Ans-hla-B
second most diverse loci Correct Ans-DRB
HLA evolve through: Correct Ans-gene conversion - short distance or abortive genetic
recombination
DR2 split into Correct Ans-DR15 &DR16
DR3 split into Correct Ans-DR17 and DR18
DR5 split into Correct Ans-DR11 and DR12
DR6 split into Correct Ans-DR13 and DR14
DR51 is linked to Correct Ans-DR2, DR15 and DR16
DR53 is linked to Correct Ans-DR4, DR7(null), DR8 and DR9
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