Exam (elaborations)
OST 575 Exam 3 Cirrhosis With Complete Solution
- Course
- Institution
OST 575 Exam 3 Cirrhosis With Complete Solution...
[Show more]
Content preview
OST 575 Exam 3 Cirrhosis With Complete SolutionDistortion of the hepatic vasculature causing shunting of portal and arterial blood
supply directly into hepatic outflow (central veins) and the compromise of exchange
between hepatic sinusoids and the adjacent liver parenchyma (i.e hepatocytes) is
characteristic of what liver disorder? - ANSWER Liver cirrhosis
What are the clinical consequences of liver cirrhosis? - ANSWER impaired *hepatocyte*
function
increased intrahepatic resistance (portal hypertension)
development of *hepatocellular carcinoma (HCC)*
What are the major complications of Liver cirrhosis? - ANSWER variceal hemorrhage
Ascites
Spontaneous bacterial peritonitis
hepatic encephalopathy
hepatocellular carcinoma
How does portal hypertension occur? - ANSWER increase in hepatic venous pressure
gradient
increase in resistance to portal venous outflow
What is the term used to describe the accumulation of fluid within the peritoneal cavity?
- ANSWER Ascites (MOST common complication of cirrhosis)
How do ascites develop? - ANSWER development of *portal hypertension* causes
sodium retention which leads to FLUID retention
, What is the term used to describe an infection of pre-existing ascitic fluid WITHOUT
evidence for an intra-abdominal secondary source, such as a *perforated viscous*? -
ANSWER Spontaneous bacterial peritonitis
When is spontaneous bacterial peritonitis most commonly seen? - ANSWER in setting of
END-stage liver disease
What are the clinical manifestations of Spontaneous bacterial peritonitis? - ANSWER
fever
abdominal pain
altered mental status
What is the most common bacterial cause of Spontaneous bacterial peritonitis? -
ANSWER E. coli
How can one tell the difference between spontaneous bacterial peritonitis and a
perforated viscous? - ANSWER perforated viscous = more than 2 bacterial organisms
found
spontaneous bacterial peritonitis = 1 bacteria
How does one diagnose and treat spontaneous bacterial peritonitis? - ANSWER Ascite
fluid bacterial culture OR elevated ascitic fluid absolute PMN leukocyte count (>250)
*antibiotic treatment*
What is Hepatorenal syndrome? - ANSWER development of renal failure in a patient with
advanced liver disease due to cirrhosis, severe alcoholic hepatitis, acute liver failure, or
even a metastatic tumor
What plays a central role in the hemodynamic changes and decline in renal function in
hepatorenal syndrome? - ANSWER Arterial vasodilation in *splanchnic circulation*
triggered by portal hypertension
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Easton. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
83750 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now