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OST 575 Understanding LFTs Exam 3 With Complete Solution
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OST 575 Understanding LFTs Exam 3 With Complete Solution...
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OST 575 Understanding LFTs Exam 3 With Complete SolutionWhat are the enzyme tests for liver damage? - ANSWER Transaminase (AST, ALT)
Alkaline phosphatase
gamma glutamyl transpeptidase (GGT)
What lab levels are tested to determine how well the liver is functioning? - ANSWER
Albumin
Prothrombin time
What can also be tested to detect if there is liver damage that is NOT an enzyme and can
be detected based on physical presentation? - ANSWER bilirubin
What are some general symptoms of liver disease? - ANSWER JAUNDICE
arthralgias
myalgias
*rash*
anorexia
weight loss
muscle wasting
*pruritis*
What are the stigmata of liver disease? - ANSWER Spider angioma
ascites
palmar erythema
jaundice/ sclera icterus
gynecomastia
, asterixis
encephalopathy
What are some common meds that can cause an *increase in LFTs*? - ANSWER NSAIDs
Antibiotics
*Statins*
antiepileptics
anti TB meds
*herbal remedies*
The transaminase enzymes (AST, ALT) are sensitive indicators for what? - ANSWER
hepatocellular damage or interference with bile flow
What transaminase enzyme, AST or ALT, is more specific for the liver? - ANSWER ALT
What is a downfall of using AST and ALT values to assess liver disease? - ANSWER Does
NOT measure liver function
If BOTH AST and ALT are increased >1000 (high), what are some possible causes? -
ANSWER *Hepatitis (acute, viral)*
*Autoimmune hepatitis*
Hep B
Drugs (acetaminophen)
shock liver (ischemic liver from decreased blood flow)
What are the values of AST and ALT that indicate alcoholic hepatitis? - ANSWER AST >
ALT (2:1 ratio)
*overall though, not more than 300*
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