N115 Take Home Midterm | Questions And Answers | Verified Study Solutions 2024/2025
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Course
N115
Institution
N115
N115 Take Home Midterm | Questions And Answers | Verified Study Solutions 2024/2025
Which one of the following is not a major feature of an ideal drug?
a. demonstrated effectiveness
b. covalent interaction with receptor
c. receptor selectivity
d. no adverse effects ANS ANS: B
Variabilit...
N115 Midterm Verified Questions And Answers
Preclinical studies Are done on ANS animals
The intensity of a drug response is dependent on ANS the site of the effect
drugs given by oral route may have a significantly higher ANS first pass effect
all true ANS A drug that is bound to plasma protein Is not pharmacological active.
A bound drug can be displaced from the protein by another drug
Only a free drug is filtered and excreted by glomerulus
bioavailibility ANS IV=100% oral is less, the fraction of the oral dose present
cytochrome p450 ANS Inducers= increased drug metabolism necessitating higher doses
(decrease half life)
Inhibitors cause the opposite so decreased drug metabolism (increase half life) so lower doses
Newer generation anticonvulsants have ANS fewer adverse effects
Benzodiazepines might be used in all of the following clinical situations ANS a child with severe
generalized seizures
depressed patient with insomnia and nightmares
sedation of patient for minor plastic surgery in office (not parkinsons)
Adverse effects of selective serotonin reuptake inhibitors (SSRI's) ANS sedation
increased blood glucose, metabolic syndrome
increased libido
, a patient taking lithium for bipolar disorder, the nurse must be aware of ANS Effectiveness takes
1-3 weeks, Hand tremor may occur at therapeutic doses, Compliance must be considered, Monitoring
blood levels is important
three most important properties of an ideal drug ANS effectiveness, safety and selectivity
pharmacokinetics ANS Site of adminstration to circulation and absorption. movement of the drug
through the body
The following antimicrobials is/are effective against community acquired MRSA ANS
Cefaroline (Teflaro)
Vancomycin
Antiemetic drugs target your cholingeric receptors has musculocholingeric effects, serotonin effects,
and dopamine effects ANS has musculocholingeric effects, serotonin effects, and dopamine
effects
Antihistamines/anticholinergics for motion sickness ANS diphenhydramine (Benadryl)
promethazine (Phenergan)
meclizine (Dramamine, Bonine)
Pepto bismal is not one
Glucocorticoids and cannabinoids may be used for what ANS May be used for chemo induced
nausea and vomiting
Albuterol (Proventil), a beta-2 selective agonist, is an example of ANS a drug that acts on the
membrane surface receptor
acidification of the urine by ascorbic acid (vitamin c) will improve the elimination of ANS weak
bases like morphine
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