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Exam (elaborations)

OCEMS Pharmacology - Drug Guide Questions and Correct Verified Answers Latest Version

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Adenosine Classification Antiarrhythmic Adenosine Mech of Action Depress automaticity in sinus node and Purkinje fibers Slows AV conduction and interrupts reentry pathways thru AV node Immed onset w/ duration less than 10 sec Adenosine Indications Narrow complex tachycardia w/ reg...

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  • October 14, 2024
  • 72
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • OCEMS
  • OCEMS
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1 | P a g e | © copyright 2024/2025 | Grade A+




OCEMS Pharmacology - Drug
Guide Questions and Correct
Verified Answers Latest Version
Adenosine Classification


✓ Antiarrhythmic




Adenosine Mech of Action


✓ Depress automaticity in sinus node and Purkinje fibers



✓ Slows AV conduction and interrupts reentry pathways thru AV node



✓ Immed onset w/ duration less than 10 sec




Adenosine Indications


✓ Narrow complex tachycardia w/ reg rhythm and rate >/= 150 in

conscious pt w/ complaint of mild chest discomfort, lightheadedness or

diaphoresis AFTER Valsalva attempt




Adenosine contraindications




Master01 | September, 2024/2025 | Latest update

, 1 | P a g e | © copyright 2024/2025 | Grade A+

✓ Known adenosine hypersensitivity, 2nd or 3rd degree AV block w/o

functioning pacemaker




Adenosine dosage form


✓ 3mg/1ml (12mg/4ml prefill)




Adenosine adult dose


✓ 12mg rapid IVP in a port closest to patient followed by rapid 10ml NS

flush; may repeat 12 mg rapid IVP once after 3 minutes if tachycardia

>/= 150 persists




Adenosine ped dose


✓ BASE HOSPITAL ORDER: 0.2mg/kg rapid IVP in a port closest to patient

followed by a rapid 5ml NS flush; may repeat with 0.2mg/kg rapid IVP in

2 minutes if tachycardia persists




Adenosine side effects




Master01 | September, 2024/2025 | Latest update

, 1 | P a g e | © copyright 2024/2025 | Grade A+

✓ Chest pain/pressure,

✓ Hypotension,

✓ Transient PAC/PVCs,

✓ Transient bradycardia/sinus arrest,

✓ Metallic taste,

✓ Throat tightness,

✓ Facial flushing




Adenosine Precautions/comments




Master01 | September, 2024/2025 | Latest update

, 1 | P a g e | © copyright 2024/2025 | Grade A+

✓ Start IV in AC vein



✓ Drug is metabolized in 10 seconds



✓ Must flush by injecting the NS flush, running the IV wide open is not an

adequate flush



✓ History of "sick sinus" syndrome, 2nd or 3rd degree heart block without

pacemaker **reactive airway disease (asthma/COPD) may have

bronchospasm



✓ Does not convert atrial flutter or fibrillation;



✓ Persantine (Dipyridamole) and Tegretol can cause a heart block-need

to use a lower dose



✓ Due to denervation of heart, use with extreme caution in cardiac

transplant recipients - may have persistent asystole



✓ Theophylline preparations can render adenosine ineffective, may need

a higher dose

Master01 | September, 2024/2025 | Latest update

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