Test bank for Tietz Fundamentals of Clinical Chemistr
and Molecular Diagnostic
8th Edition by Nader Rifai, PhD
Chapters 1 - 4
,TietzkFundamentalskofkClinicalkChemistrykandkMolecularkDiagnosticsk8thk EditionkTestkBank
Tablekofkcontents:
I.kPrincipleskOfkLaboratorykMedicine
Chapterk1.kClinicalkChemistry,kMolecularkDiagnostics,kandkLaboratorykMedicine
Chapterk2.kSelectionkandkAnalyticalkEvaluationkofkMethodsk—kWithkStatisticalkTechniques
Chapterk3.kClinicalkEvaluationkofkMethods
Chapterk4.kEvidence-BasedkLaboratorykMedicine
Chapterk5.kEstablishmentkandkUsekofkReferencekValues
Chapterk6.kSpecimenkCollection,kProcessing,kandkOtherkPreanalyticalkVariables
Chapterk7.kQualitykManagement
II.kAnalyticalkTechniqueskAndkInstrumentation
Chapterk8.kPrincipleskofkBasickTechniqueskandkLaboratorykSafety
Chapterk9.kOpticalkTechniques
Chapterk10.kElectrochemistrykandkChemicalkSensors
Chapterk11.kElectrophoresis
Chapterk12.kChromatography
Chapterk13.kMasskSpectrometry
Chapterk14.kEnzymekandkRatekAnalyses
Chapterk15.kImmunochemicalkTechniques
Chapterk16kAutomation
Chapterk17.kPoint-of-CarekInstrumentation
III.k Analytes
Chapterk18.kAminokAcids,kPeptides,kandkProteins
Chapterk19.kSerumkEnzymes
Chapterk20.kTumorkMarkerskandkCancerkGenes
Chapterk21.kKidneykFunctionkTestsk—kCreatinine,kGFR,kUrea,kandkUrickAcid
Chapterk22.kCarbohydrates
Chapterk23.kLipids,kLipoproteins,kApolipoproteins,kandkOtherkCardiackRiskkFactors
Chapterk24.kElectrolyteskandkBloodkGases
Chapterk25.kHormones
Chapterk26.k CatecholamineskandkSerotonin
Chapterk27.k Vitamins,kTracekElements,kNutritionalkAssessment
Chapterk28.kHemoglobin,kIron,kandkBilirubin
Chapterk29.kPorphyrinskandkPorphyrias
Chapterk30.kTherapeutickDrugskandkTheirkManagement
Chapterk31.kClinicalkToxicology
Chapterk32.k ToxickMetals
IV.k Pathophysiology
Chapterk33.kDiabetes
,Chapterk34.k CardiovascularkDisease
Chapterk35.kKidneykDisease
Chapterk36.k PhysiologykandkDisorderskofkWater,kElectrolyte,kandkAcid-BasekMetabolism
Chapterk37.kkLiverkDisease
Chapterk38.k GastrointestinalkandkPancreatickDiseases
Chapterk39.kkDisorderskofkBonekandkMineralkMetabolism
Chapterk40.kkDisorderskofkthekPituitarykGland
Chapterk41.k DisorderskofkthekAdrenalkCortex
Chapterk42.k ThyroidkDisorders
Chapterk43.k Reproduction-RelatedkDisorders
Chapterk44.kkPregnancykandkPrenatalkTesting
Chapterk45.k NewbornkScreeningkandkInbornkErrorskofkMetabolism
Chapterk46.kPharmacogenetics
V.k MolecularkDiagnostics
Chapterk47.kPrincipleskofkMolecularkBiology
Chapterk48.kNucleickAcidkTechniqueskandkApplications
Chapterk49.kGenomeskandkNucleickAcidkAlterations
, Chapterk01:kClinicalkChemistry,kMolecularkDiagnostics,kandkLaboratorykMedicinekTe
stkBank
MULTIPLEkCHOICE
1. Ankindividualkworkingkinkakclinicalkchemistryklaboratorykiskmarriedktokaksaleskrepresentativek
whokworkskforkakcompanykthatksellskchemistryklaboratoryksupplies.kWhenktheklaboratorykman
agerkrequestskaklistkofkneededksupplies,kcostkofksupplies,kandkvendors,kthiskindividualkonlykreco
mmendskthekspouse’skcompanykaskthekvendor.kThiskiskconsideredktokbeka(n):
a. accountingkissue.
b. possiblekconflictkofkinterest.
c. maintenancekofkconfidentialitykissue.
d. problemkwithkresourcekallocation.
ANS:k B
Concernkhaskbeenkraisedkoverkthekinterrelationshipskbetweenkpractitionerskinkthekmedicalkfieldk
andkcommercialksupplierskofkdrugs,kdevices,kequipment,ketc.,ktokthekmedicalkprofession.
Similarly,krelationshipskhavekbeenkscrutinizedkbetweenkclinicalklaboratorianskandkmanufacturer
skandkproviderskofkdiagnostickequipmentkandksupplies.kThesekconcernskledkthekNationalkInstitut
eskofkHealthk(NIH)kink1995ktokrequirekofficialkinstitutionalkreviewkofkfinancialkdisclosurekbykres
earcherskandkmanagementkofksituationskinkwhichkdisclosurekindicateskpotentialkconflictskofkinter
est.
DIF: 1 REF:kkkPagek4-5 OBJ:k 6k|k7
2. Akpatientkvisitskherkphysiciankstatingkthatkherkprescribedkpainkillerkisknotkworkingktokreducek
thekpainkfollowingkherkrecentksurgery.kAkfriendkofkthekpatientkclaimskthatktheksamekpainkillerk
―workedkwonders‖ktokreducekherkpainkafterktheksameksurgery.kThekphysiciankstateskthatkthek
differencekinkthekeffectkofkthekdrugkmightkbekcausedkby
,kwhichkiskstudiedkinkpharmacogenetics.
a. epidemiology
b. ankinheritedkdisease
c. akconflictkofkinterest
d. akgenetickvariationkinkdrug-metabolizingkenzymes
ANS:k D
Pharmacogeneticskiskthekstudykofkthekgenetickvariationkofkdrugkmetabolismkbetweenk
individuals.
DIF: 1 REF:kkkPagek3 OBJ:k 1
3. Johnkworkskinkakmolecularkdiagnosticsklaboratorykandkreceiveskakbloodksamplekthatkhaskthek
namekofkakclosekfriendkprintedkonkthekbar-
codedklabel.kThekgeneticktestkthatkiskorderedkonkthekfriend’sksamplekwouldkprovidekdiagnosti
ckinformationkaboutkakdisorderkthatkhaskakpoorkprognosis,kandkthektestkiskusuallykperformedk
bykJohn.kHekaskskakfellowkemployeektokanalyzektheksamplekforkhimkandknotkdivulgekthekresul
ts.kThiskethicalkissuekconcerns:
a. confidentialitykofkpatientkgenetickandkmedicalkinformation.
b. akconflictkofkinterest.
c. resourcekallocation.
d. diagnostickaccuracy.
