BioChem WGU C785 Module 1 all
questions and answers already graded
A+| Updated & Verified | 2024
The LCT gene codes for Lactase, which is responsible for the breakdown of lactose. How is the Lactase
activity increased? - ✔✔the presence of lactose causes nucleosomes to separate, exposing the LCT gene
Histone proteins can be chemically modified by addition of methyl group. As a result, nucleosomes
pack tightly and the process of transcription is decreased at those DNA sites - ✔✔True
When the wrong nucleotide is added to a newly forming DNA strand during DNA replication: -
✔✔distortion of the double helix retains its shape due to the pairing of A with T and G with C
Mutation to the DNA strand that consists of a nucleotide sequence: 5'- CTG ACG TAT CTT AAT -3' -
✔✔5'-CTG ACG TAA CTT AAT-3'
A patient with xeroderma pigmentosum is prone to developing multiple skin cancers starting in
childhood. This occurs because of a mutation in a gene that codes for enzymes that help repair DNA
damage through the nucleotide excision repair (NER) pathways. How does the NER differ from other
, repair mechanisms? - ✔✔The error in one strand of DNA is removed as well as several nucleotides on
either side of the error. The gap that was removed is filled in by DNA polymerase.
Steps in the (BER) base excision repair: - ✔✔1. Removal of the damage by excising part of one strand
to leave a gap
2. Ligation to restore continuity of the DNA backbone
3. Recognition of the damage
Used in (PCR) Polymerase Chain Reaction: - ✔✔1. DNA template
2. DNA Nucleotides
3. Primer
DNA polymerase is involved in DNA replication. DNA polymerase - ✔✔adds nucleotides to the new
NDA strand in the 5'-3' direction
TRH is a very small molecule - 3 amino acids long - that helps regulate the amount of thyroid hormone
produced by the thyroid gland. Although it is a small polypeptide, the mRNA that is created during
transcription of the TRH gene is actually many, many nucleotides longer than the 9 nucleotides that
would be required for a 3 amino acid polypeptide. What might reasonably explain why the actual mRNA
produced during transcription is so much longer than the minimum 9 nucleotides required to code for
the 3 amino acids? - ✔✔Introns are removed from the mRNA after transcription of the gene that occurs
What would be the resulting mRNA sequence from this template strand: 5'-ACA GCT GTC-3' - ✔✔5'-GAC
AGC UGU-3'
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