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Advanced Pathophysiology Exam 2 Q&A Latest Verified Solution (HELPFUL).
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  • Advanced pathophysiology
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what differentiates benign tumors from malignant tumors - - -grow slowly -have well-defined capsule -are not invasive -are well differentiated; look like the tissue from which they arose -have a low miotic index; dividing cells are rare -do not metastasize What differentiates malignant tum...

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  • October 16, 2024
  • 26
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • Advanced pathophysiology
  • Advanced pathophysiology

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Advanced Pathophysiology Exam 2 Q&A Latest
Verified Solution (HELPFUL)


A mother is a carrier for x-linked recessive Emery-Derfuss muscular dystrophy gene. The father has
not been tested but does not exhibit the phenotype that would normally be showing at his age (upper
and lower extremity weakness, soreness, and arrhythmias). What does their offspring chance of
inheritance look like?

a. Non-carriers 50%, Carrier 25%, Affected 25%

b. Non-carriers 25%, Carrier 50%, Affected 25%

c. Non-carriers 25%, Carrier 25%, Affected 25%

d. Affected 50%, Non-affected 25% - ✔✔✔ - a



If two heterozygous individuals mated and their first three children expressed a phenotype for a
dominant trait, which of the following would be true?

a) their next child would have the dominant trait

b) their next child would have the recessive trait

c) there is a 25% chance their next child would show the recessive trait

d) they cannot have a child with the recessive trait - ✔✔✔ - c



In an autosomal dominant disorder, mom is affected, father is unaffected. The inheritance chance for
offspring is:

a. Affected 50%, Unaffected 50%

b. Affected 25%, Unaffected 75%

c. Affected 75%, Unaffected 25%

d. Affected 100%, Unaffected 0% - ✔✔✔ - a

,In an autosomal recessive disorder, mom is non-carrier, father is affected. The offspring's chance of
inheritance is:

a. Carrier 25%, Non-carrier 75%, Affected 0%

b. Carrier 25%, Non-carrier 25%, Affected 50%

c. Carrier 100%, Affected 0%

d. Carrier 75%, Non-carrier 25%, Affected 0% - ✔✔✔ - c



In an autosomal recessive disorder, mom is carrier, father is affected. The offspring's chance of
inheritance is:

a. Carrier 25%, Non-carrier 75%, Affected 0%

b. Carrier 25%, Non-carrier 25%, Affected 50%

c. Carrier 25%, Affected 75%

d. Carrier 50%, Affected 50% - ✔✔✔ - d



In an x-linked dominant disorder, mom is affected, father is unaffected. The offspring's chance of
inheritance is:

a. Carrier 25%, Non-carrier 75%, Affected 0%

b. Affected 50%, Non-affected 50%

c. Affected 75%, Non-affected 25%

d. None of the above - ✔✔✔ - B



In an x-linked dominant disorder, mom is affected, father is affected. The offspring's chance of
inheritance is:

a. Affected 25%, Non-affected 25%

b. Affected 50%, Non-affected 50%

c. Affected 100%, Non-affected 0%

d. Affected 75%, Non-affected 25% - ✔✔✔ - d



In an x-linked recessive disorder, mom is affected, father is non-carrier. The offspring's chance of
inheritance is:

, a. Non-carrier 25%, Carrier 25%, Affected 50%

b. Non-carriers 0%, Carrier 50%, Affected 50%

c. Non-carrier 25%, Carrier 25%, Affected 50% - ✔✔✔ - b



A husband and wife are both carriers for phenylketonuria. What are the chances they will conceive
an offspring with that disease?

a) 0%

b) 25%

c) 50%

d) 75% - ✔✔✔ - B



Who are more likely to suffer from X-linked diseases and why?

a) Females, because they have two X-chromosomes and are therefore more likely to inherit one with
a disease

b) males, because they have only one X-chromosome and if it is mutated they have no back up copy

c) females, because one of their X-chromosomes is deactivated

d) both males and females are equally likely to suffer from X-linked disorders - ✔✔✔ - B



Which of the following is true of autosomal recessive inheritance?

a) consanguinity is never present

b) males and females are effected equally

c) the disease runs through the whole family

d) one third of offspring are affected - ✔✔✔ - B



Broken Chromosome with lost DNA

a) deletion

b) duplication

c) inversion

D) translocation - ✔✔✔ - A

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