10/16/24, 3:29 PM Nurs 615 Exam /NURS 615-Pharm Exam 4 complete Questions & Answers (100% verified solutions)/2024-2025 update Flas…
Nurs 615 Exam /NURS 615-Pharm Exam 4
complete Questions & Answers (100% verified
solutions)/2024-2025 update
Terms in this set (81)
Patients with cystic fibrosis are often prescribed
How will you prescribe enzyme replacement for pancreatic secretions each
lipase, protease, and replacement drug has amylase, lipase and protease
amylase components? components, however the drug is prescribed in units
of lipase
Surgical resection of the tumor is the first treatment
of choice either my open laparotomy or
laparoscopy either surgical option requires prior
treatment of nonspecific irreversible adrenergic
What is the medication of
adraonoreceptor blocker phenoxybenzamine or a
choice for hypertensive
shorter acting alpha antagonists, prazosin, terazosin,
crisis with
and doxazosin. Mainly use phenozibenamine in
pheochromocytoma?
practice. Doing so promotes the surgery to proceed
while minimizing the likelihood of severe
intraoperative hypertension which is likely when the
tumor is manipulated.
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(Intermediate Acting) NPH
Onset-60-90 min after administration,
Peak 48 hrs
Duration 10-18 hrs.
(Short Acting) Regular Onset 30-60 min
Peak 2-4 hrs
What is the onset of Duration 6-10 hrs
action, peak of action,
and duration of action of (Long Acting) Aspart, Lispro, Glulisine
each insulin preparation? Onset less than 15 min
Peak 1-2 hrs
Duration 3-6 hrs
(Long Acting) Glargine, Detemir
Onset 1-2 hrs
Peak NO PEAK
Duration 24 hrs
Hypoglycemia- dizziness, confusion, diaphoresis,
tachycardia
Identify the symptoms of
Hyperglycemia- polyphagia, polydipsia, polyuria,
hypoglycemia,
blurred vision, and fatigue
hyperglycemia, and
Ketoacidosis- hallmark symptoms include acetone
ketoacidosis.
breath like nail polish remover or fruity breath. Also
abdominal pain, nausea, vomiting and sob.
When changing from The initial dose of glargine is reduced by 20% to
NPH to glargine insulin, prevent hypoglycemia.
how will you adjust the
patient's dose?
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Decreases hyperglycemia by decreasing hepatic
glucose production called hepatic
gluconeogenesis. The average person with type 2
diabetes has three times the rate of
gluconeogenesis, metformin treatment reduces this
by over 1/3rd. The molecular mechanism of
metformin isn't completely understood. In addition
to suppressing hepatic glucose production,
How does metformin
metformin increases insulin sensitivity, enhances
work?
peripheral glucose uptake by inducing the
phosphorilization of glu4 enhancer factor,
decreases insulin induced suppression of fatty acid
oxidation, and decreases absorption of glucose
from the GI tract. Also of note* Metformin helps
reduce LDL cholesterol and triglyceride levels and
is not associated with weight gain, in some people
it helps promote weight loss*
Metformin is not metabolized, it is cleared from the
body by tubular secretion and is secreted
What diagnostic testing is
unchanged in the urine. Metformin is undetectable
required before and
in blood plasma within 24 hrs of a single oral dose
throughout therapy with
the average elimination half-life in plasma is 6.2 hrs
metformin?
as it is secreted in the urine you should check a
serum crt to assess renal function.
The mechanism of DDP-4 inhibitors is to increase
incretin levels incretin are GLP1 and GIP which inhibit
What is the action of
glucagon release in which in turn increases insulin
gliptin?
secretion, decreases gastric emptying, and
decreases blood glucose levels
They bind directly to a receptor in the pancreatic
How do GLP agonists beta cell. These agents work in the same pathway as
work? the DPP-4 inhibitors as mentioned above but are
generally considered more potent.
When should exenatide 60 minutes prior to the morning and evening meal
be administered?
How will you assess for Signs of a Cold or flu including fever and sore throat
granulocytopenia?
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Agranulocytosis, thrombocytopenia, and fulminant
What are the adverse
liver failure as stated above, pt's on PTU when they
effects of
develop fever or sore throat, it would be important
propylthiouracil?
to check a CBC preferably with a smear and a diff.
What are the adverse Tachycardia and angina in the elderly
effects of levothyroxine?
A patient develops a Methimazole for one month then radioactive iodine
toxic goiter. What is the (p. 641)
recommended
treatment?
What are the adverse PTU- Fatal agranulocytopenia look for fever and
effects of PTU and sore throat and TEMPORARY ALOPECIA
methimazole?
Bone undergoes constant turnover and is kept in
balance by osteoblasts creating bone and
osteoclasts destroying bone. Bisphosphonates
inhibit the digestion of bone by encouraging
osteoclasts to undergo apoptosis or cell death
there by slowing bone loss. Oral bisphosphonates
can cause upset stomach and inflammation as well
as erosion. Erosions of the esophagus which is the
What is the action of
main problem of oral and containing preparations.
biphosphonates?
This can be prevented by sitting upright for 30-60
minutes after taking the medication. If the patient
does develop some type of gastric distress, give
them oral 30ml of Maalox 3 hrs after taking it. IV
bisphosphonates can give fever and flu like
symptoms after the first infusion which is thought to
occur because of their potential to activate human T
cells
Which infant formula is Prosobee
linked to impairment of
thyroxine absorption?
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