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APEA Endo/exam/revision study guide/questions and answers/verified 100%
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APEA Endo/exam/revision study guide/questions and answers/verified 100%APEA Endo/exam/revision study guide/questions and answers/verified 100% When patients administer regular insulin (Humulin R U-500), they should be taught: - correct answers-10 units of Humulin R U-500 is equal to 10 units o...

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  • October 17, 2024
  • 11
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • apea endoexamrevision study guidequestions and

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APEA Endo/exam/revision study guide/q
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Whenuspatientsusadministerusregularusinsulinus(HumulinusRusU-
500),ustheyusshouldusbeustaught:us-uscorrectusanswers-10usunitsusofusHumulinusRusU-
500usisusequalustous10usunitsusonusausU-500usinsulinussyringe.
Radioiodineustherapyusisussafeustousadministerusto:us-uscorrectusanswers-Aus30-year-
oldusmanuswhousdesiresusnaturalusfatherhood-
usedustoustxushyperthyroidismusandusdoesusnotuscauseusinfantilityusorusbirthusdefectsusinustheusoffs
pringusofustx'duspts
AusptuswhoushasusAddison'susdiseaseushasusreceivedusausprescriptionusforusfludrocortisone.usFlu
drocortisoneusactsusby:us-uscorrectusanswers-Regulatingussaltusanduswaterusbalance-
mineralocorticoidusindicatedusasuspartialusreplacementustherapyusforusptsuswithusprimaryusorus2n
daryusadrenocorticalusinsufficiency
MethimazoleusforustheustxusofusGraves'usdiseaseusisuscontraindicatedusinuspts:us-
uscorrectusanswers-Whousareuspregnant-

canuscauseusfetalusharmuswhenusadministered,uscanusreadilyuscrossustheusplacentalusmembrane
s
Whichusofustheusfollowingusmedicationsusmayuscauseusgynecomastia?us-uscorrectusanswers-
Enalaprilus(Vasotec)-ACEusinhibitorsusmayuscauseusgynecomastia
Ausptusisusstartedusonusaussulfonylureaus(i.e.usglyburide).usTheusNPusinformsustheusptusthatussulfonyl
ureasusareuslikelyusto:us-uscorrectusanswers-Reduceusmicrovascularusevents-alsouslowusinuscost


Disadvantages-produceushypoglycemiausanduscauseusweightusgain
Thiazolidinedioneus(TZD)usmedications:us-uscorrectusanswers-Increaseusinsulinussensitivity-
byusactingusonusadipose,usmuscleus&usliverustousincreaseusglucoseusutilizationusandusdecreaseusgl
ucoseusproduction
Ptsustakingusdipeptidyl-peptidase-4us(DDP-
IV)usinhibitorsusforustheustxusofusT2DMusdousNOTusroutinelyusneedustousbeusmonitoredusfor:us-
uscorrectusanswers-Weightusloss-

Januvia,usOnglyza,usTradjentausnotuslikelyustouscauseusweightuslossusorusweightusgain
TheusexpectedushemoglobinusA1Vusreductionusforusptsuswhousareusstartedusonusdipeptidyl-
peptidase-4us(DDP-IV)usinhibitorsussuchusasussitagliptinus(Januvia)usis:us-uscorrectusanswers-
0.6%

, DDP-IVusinhibitorsussuchusasusalogliptinus(Nesina):us-uscorrectusanswers-
Suppressusglucagonussecretionusandusincreaseusinsulinussecretionus


Sulfonylurea-stimulateustheusreleaseusofusinsulinusfromusfunctioningusbetauscells


Biguanides-
decreaseushepaticusglucoseusproduction,usdecreaseusintestinalusabsorptionusofusglucose,usandu
simproveusinsulinussensitivity



Priorustoustheusadminusofusmethimazoleus(Tapazole)ustheusNPusshouldusobtainusausbaseline:us-
uscorrectusanswers-CBC-txusforushyperthyroidism,usCBCus&usliverusprofileusshouldusbeusobtained



Ausptusisusstartedusonusexenatideus(Byetta)usforusT2DM.usByettausshouldusbeusd/c'dusifustheusptusexhi
bits:us-uscorrectusanswers-Persistentusabduspain,usradiatingustoustheusback-
monitoredusforussxusofusacuteuspancreatitis
Sulfonylureasussuchusasusglyburideus(Micronase)usareusextensivelyusmetabolized:us-
uscorrectusanswers-Inustheusliver-primarilyusbyusCYPus450



Aus48-year-
oldusptusisusstartedusonusmetforminus(Glucophage)usforusT2DM.usTheusmaximumusexpectedushe
moglobinusA1Cusreductionusafterusinitiationusofusthisusmedicationusis:us-uscorrectusanswers-2%-
ususualusexpectedusdecreaseusinusA1Cusisus1-2%



Insulinsusrecommendedusforususeusinusinsulinuspumpusdeliveryussystemsusinclude:us-
uscorrectusanswers-Apidraus&usHumalog-

onlyusrapidusactingusinsulinsusareussafeusforuscontinuoususIVususe
TheusgenericusnameusforusVictozausis:us-uscorrectusanswers-Liraglutide-GLP-1usagonists
Ausptuswhousisusstartedusonusausglucagon-likeuspeptideus(GLP-
1),ussuchusasusVictoza,usshouldusbeusinformedusthatusthisusclassusofusmedicationsusmay:us-
uscorrectusanswers-Increaseussatiety-delayusgastricusemptyingus&uspromoteusweightusloss



Ptsuswhousareusreceivingusradioiodineustherapyusforushyperthyroidismusshouldusbeusadvisedusto:u
s-uscorrectusanswers-Avoiduscontactuswithusyounguschildrenusforusseveralusdays-

radiationusemitsusfromustheusbodyusavoiduskidsus&uspregnantuswomen
Ptsustakingusthiazolidinedioneus(TZD)usmedicationsusshouldusbeusmonitoredusfor:us-
uscorrectusanswers-Fluidusretentionus&usweightusgain-

mayusprecipitateusorusexacerbateusHFusinussomeusptsusbyuscausingusdose-
relatedusfluidusretention
Levothyroxineususeusinustheus1stustrimesterusofuspregnancy:us-uscorrectusanswers-
Mayusrequireusanusincreaseusinusdose-
dueustousalterationsusofusendogenoususmaternalusthyroidushormones

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