PATH 3610 Midterm 3 Exam | Verified with 100% Correct Answers Which of the following represents the end stage of wound repair? a. proliferation and mobilization of fibroblasts b. dominance of fibrocytes and abundant collagen c. proliferation of capillary buds and formation of abundant capillarie...
Which of the following represents the end stage of wound repair?
a. proliferation and mobilization of fibroblasts
b. dominance of fibrocytes and abundant collagen
c. proliferation of capillary buds and formation of abundant capillaries
Granulation tissue refers to which of the following?
a. inflammatory tissue formed in response to the presence of some indigestible
organism or particle
b. tissue formed in chronic inflammation, characterized by infiltration of mononuclear
cells and scarring
c. fibrovascular tissue which has a role in healing of large wounds
Epithelioid cells are derived from:
a. monocytes
b. lymphocytes
c. squamous epithelium
When inflammation and necrosis destroy permanent body cells such as neurons in
the brain, the result is:
a. chronic inflammation
b. scar tissue
c. regenerative repair to re-establish the normal state
Repair by proliferation of connective tissue is the definition of:
a. keloid
b. contracture
c. fibrosis or scarring
Which of the following statements is not true of granulomatous inflammation?
a. it develops when macrophages phagocytose an "indigestible" agent
b. an active B cell - mediated immune response must occur
c. it is characterized by the presence of epithelioid cells, mononuclear cells and giant
cells
,Which of the following is a cause of non-granulomatous chronic inflammation?
a. foreign material such as talc or sponge fibres
b. chronic viral infections
c. chronic mycobacterial infections
Amyloid consists of:
a. insoluble, beta-pleated fibrillar protein
b. immunoglobulin light chains
c. amorphous material deposited in tissues
Cells which are reversibly post-mitotic and can divide if necessary to allow regeneration
are:
a. cells of the basal layer of the epidermis
b. cells lining the alimentary tract
c. parenchymal cells of the liver, kidney and pancreas
Granulation tissue is more prominent in:
a. wound healing by first intention
b. wound healing by second intention
c. chronic inflammation
What does tissue resolution mean?
return of tissue to normal state
What does tissue regeneration mean?
when damage is too great, the replacement of necrotic parenchymal tissue by new
parenchymal cells
Connective tissue deposition scar formation:
If the injured tissues are incapable of complete restitution, or if the supporting structures
of the tissue are severely damaged, repair occurs by the laying down of connective
(fibrous) tissue, a process that may result in formation of a scar
Explain the role of tissue resolution and regeneration in Acute versus chronic
inflammation:
In acute inflammation, resolution & regeneration is possible, but in chronic inflammation,
only regeneration is possible because true resolution is not possible.
Explain tissue regeneration in labile tissue:
Is some tissues, there are cells that are constantly being lost and regenerated. These
types of tissues include hematopoietic cells in the bone marrow and many surface
epithelia, such as the basal layers of the squamous epithelia of the skin, oral cavity,
, vagina, and cervix.
♣ These cells have a short intermitotic life (resting life)
Explain tissue regeneration in stable cells:
normally in the G0 stage of the cell cycle, and they only divide in response to injury.
This occurs in solid organs.
Explain tissue regeneration in permanent cells:
these cannot divide after fetal life. These include the nervous system and cardiac
muscle cells.
• Modern scope of permanent cell population
o Some new research has shown that some irreversible injury can be overcome via a
process referred to as a plasticity.
Name of section: What determines the rate of cell proliferation?
o Primary motivators of cell replication are proteins calls_______, which interact
with_______-dependent kinases within the nucleus and control the entry and
progression of cells through the __________
cyclins
cyclin
cell cycle
there are many systemic hormones that promote cell replication, including (2)
thyroid and growth hormone.
o Scaring occurs when:
♣ When regeneration is not possible, either when its damage to parenchymal cells, or
because the stimulus has become widespread
♣ When acute inflammatory process is not resolves, or there is ongoing tissue necrosis
in chronic inflammation
scarring is:
Replacement of normal tissue by dense collagenous connective tissue after injury, the
result of fibrosis
What is rotavirus?
Rotavirus disease is common among infants and young children. Rotavirus can cause
severe watery diarrhea, vomiting, fever, and abdominal pain. Some children with
rotavirus disease lose a lot of fluids and become very dehydrated.
Granulation tissue play a much greater role in
secondary intention
1. Morbidity:
2. Mortality:
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller NurseHenny. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $22.49. You're not tied to anything after your purchase.
